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Rational design, synthesis and in vitro evaluation of novel exo-methylene butyrolactone salicyloylamide as NF-κB inhibitor.
Sidthipong, Kulrawee; Ma, Jun; Yu, Wei Lin; Wang, Yan Feng; Kobayashi, Susumu; Kishino, Satoshi; Koide, Naoki; Yokochi, Takashi; Kato, Kuniki; Okada, Shoshiro; Umezawa, Kazuo.
Afiliación
  • Sidthipong K; Department of Molecular Target Medicine, Aichi Medical University School of Medicine, 1-1 Yazako-Karimata, Nagakute 480-1195, Japan.
  • Ma J; Shenzhen Wanhe Pharmaceutical Co., Ltd., Hi-tech Industrial Park, Nanshan District, Shenzhen, China.
  • Yu WL; Shenzhen Wanhe Pharmaceutical Co., Ltd., Hi-tech Industrial Park, Nanshan District, Shenzhen, China.
  • Wang YF; Shenzhen Wanhe Pharmaceutical Co., Ltd., Hi-tech Industrial Park, Nanshan District, Shenzhen, China.
  • Kobayashi S; Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641, Chiba 278-8510, Japan.
  • Kishino S; Department of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, 2-522-1, Kiyose, Tokyo 204-0004, Japan.
  • Koide N; Department of Microbiology and Immunology, Aichi Medical University School of Medicine, 1-1 Yazako-Karimata, Nagakute 480-1195, Japan.
  • Yokochi T; Department of Microbiology and Immunology, Aichi Medical University School of Medicine, 1-1 Yazako-Karimata, Nagakute 480-1195, Japan.
  • Kato K; Department of Molecular Target Medicine, Aichi Medical University School of Medicine, 1-1 Yazako-Karimata, Nagakute 480-1195, Japan.
  • Okada S; Department of Pharmacology, Aichi Medical University School of Medicine, 1-1 Yazako-Karimata, Nagakute 480-1195, Japan.
  • Umezawa K; Department of Molecular Target Medicine, Aichi Medical University School of Medicine, 1-1 Yazako-Karimata, Nagakute 480-1195, Japan. Electronic address: umezawa@aichi-med-u.ac.jp.
Bioorg Med Chem Lett ; 27(3): 562-566, 2017 02 01.
Article en En | MEDLINE | ID: mdl-28003138
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: 4-Butirolactona / Diseño de Fármacos / Salicilamidas / Antiinflamatorios no Esteroideos / FN-kappa B Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: 4-Butirolactona / Diseño de Fármacos / Salicilamidas / Antiinflamatorios no Esteroideos / FN-kappa B Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido