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Pregnancy-associated osteoporosis (PAO) with multiple vertebral fragility fractures: diagnosis and treatment in a young primigravid woman.
Pola, E; Colangelo, D; Nasto, L A; Pambianco, V; Autore, G; Formica, V M; Maccauro, G.
Afiliación
  • Pola E; Spinal Unit, Department of Orthopaedics and Traumatology, “A. Gemelli” University Hospital, Catholic University of Rome, Rome, Italy.
  • Colangelo D; Spinal Unit, Department of Orthopaedics and Traumatology, “A. Gemelli” University Hospital, Catholic University of Rome, Rome, Italy.
  • Nasto LA; Centre for Spine Studies and Surgery, Queen’s Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.
  • Pambianco V; Spinal Unit, Department of Orthopaedics and Traumatology, “A. Gemelli” University Hospital, Catholic University of Rome, Rome, Italy.
  • Autore G; Spinal Unit, Department of Orthopaedics and Traumatology, “A. Gemelli” University Hospital, Catholic University of Rome, Rome, Italy.
  • Formica VM; Spinal Unit, Department of Orthopaedics and Traumatology, “A. Gemelli” University Hospital, Catholic University of Rome, Rome, Italy.
  • Maccauro G; Department of Orthopaedics and Traumatology, “A. Gemelli” University Hospital, Catholic University of Rome, Rome, Italy.
J Biol Regul Homeost Agents ; 30(4 Suppl 1): 153-158, 2016.
Article en En | MEDLINE | ID: mdl-28002913
PAO is an uncommon condition affecting pregnant women during last trimester or early post-delivery period; it is often asymptomatic or presents with pain related to some acute fragility fractures. The diagnosis is often delayed or missed, the etiology remains unknown and no guidelines about treatment have been published. We present one case of PAO in a 33-year-old primigravid woman presenting acute worsening back pain. Our patient was treated with a TLSO brace, oral 25 (OH)-vitamin D supplementation and Teriparatide for 6 months. A short review of the literature has been included and useful advice about how to suspect and diagnose this uncommon disease were given in order to recognize and treat such a debilitating and severe condition for young mothers as best as possible, based on the available scientific evidences.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Complicaciones del Embarazo / Fracturas de la Columna Vertebral Tipo de estudio: Diagnostic_studies / Guideline / Risk_factors_studies Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: J Biol Regul Homeost Agents Asunto de la revista: BIOLOGIA / BIOQUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Complicaciones del Embarazo / Fracturas de la Columna Vertebral Tipo de estudio: Diagnostic_studies / Guideline / Risk_factors_studies Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: J Biol Regul Homeost Agents Asunto de la revista: BIOLOGIA / BIOQUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia