Promoter hypermethylation of <i>SHOX2</i> and <i>SEPT9</i> is a potential biomarker for minimally invasive diagnosis in adenocarcinomas of the biliary tract.

Branchi, V; Schaefer, P; Semaan, A; Kania, A; Lingohr, P; Kalff, J C; Schäfer, N; Kristiansen, G; Dietrich, D; Matthaei, H

Promoter hypermethylation of SHOX2 and SEPT9 is a potential biomarker for minimally invasive diagnosis in adenocarcinomas of the biliary tract.

Branchi, V; Schaefer, P; Semaan, A; Kania, A; Lingohr, P; Kalff, J C; Schäfer, N; Kristiansen, G; Dietrich, D; Matthaei, H.

Afiliación

Branchi V; Department of General, Visceral, Thoracic and Vascular Surgery University Hospital Bonn, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
Schaefer P; Department of General, Visceral, Thoracic and Vascular Surgery University Hospital Bonn, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
Semaan A; Department of General, Visceral, Thoracic and Vascular Surgery University Hospital Bonn, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
Kania A; Department of General, Visceral, Thoracic and Vascular Surgery University Hospital Bonn, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
Lingohr P; Department of General, Visceral, Thoracic and Vascular Surgery University Hospital Bonn, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
Kalff JC; Department of General, Visceral, Thoracic and Vascular Surgery University Hospital Bonn, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
Schäfer N; Department of General, Visceral, Thoracic and Vascular Surgery University Hospital Bonn, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
Kristiansen G; Institute of Pathology, University Hospital Bonn, Bonn, Germany.
Dietrich D; Institute of Pathology, University Hospital Bonn, Bonn, Germany.
Matthaei H; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Bonn, Germany.

Clin Epigenetics ; 8: 133, 2016.

Article en En | MEDLINE | ID: mdl-27999621

Asunto(s)

Adenocarcinoma/diagnóstico; Neoplasias del Sistema Biliar/diagnóstico; Detección Precoz del Cáncer/métodos; Proteínas de Homeodominio/genética; Septinas/genética; Adenocarcinoma/genética; Adulto; Anciano; Anciano de 80 o más Años; Neoplasias del Sistema Biliar/genética; Biomarcadores de Tumor/genética; Metilación de ADN; Epigénesis Genética; Femenino; Humanos; Masculino; Persona de Mediana Edad; Invasividad Neoplásica; Pronóstico; Regiones Promotoras Genéticas; Estudios Prospectivos

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Sistema Biliar / Adenocarcinoma / Proteínas de Homeodominio / Detección Precoz del Cáncer / Septinas Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Epigenetics Año: 2016 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania

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