Estrogen-induced SDF-1&#945; production promotes the progression of ER-negative breast cancer via the accumulation of MDSCs in the tumor microenvironment.

Ouyang, Liquan; Chang, Weilong; Fang, Bin; Qin, Jieting; Qu, Xincai; Cheng, Fanjun

Estrogen-induced SDF-1α production promotes the progression of ER-negative breast cancer via the accumulation of MDSCs in the tumor microenvironment.

Ouyang, Liquan; Chang, Weilong; Fang, Bin; Qin, Jieting; Qu, Xincai; Cheng, Fanjun.

Afiliación

Ouyang L; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Chang W; Department of General Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Fang B; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Qin J; Department of Clinical Medicine, Yichang Hospital of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Yichang 443000, Hubei, China.
Qu X; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science And Technology, Wuhan 430022, China.
Cheng F; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Sci Rep ; 6: 39541, 2016 12 20.

Article en En | MEDLINE | ID: mdl-27996037

Asunto(s)

Neoplasias de la Mama/metabolismo; Quimiocina CXCL12/metabolismo; Receptor alfa de Estrógeno/metabolismo; Estrógenos/farmacología; Células Supresoras de Origen Mieloide/citología; Microambiente Tumoral; Animales; Movimiento Celular; Quimiotaxis; Técnicas de Cocultivo; Progresión de la Enfermedad; Femenino; Fibroblastos/metabolismo; Humanos; Ratones; Ratones Endogámicos BALB C; Trasplante de Neoplasias; Proteínas Recombinantes/metabolismo; Transducción de Señal

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptor alfa de Estrógeno / Estrógenos / Quimiocina CXCL12 / Microambiente Tumoral / Células Supresoras de Origen Mieloide Límite: Animals / Female / Humans Idioma: En Revista: Sci Rep Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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