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Identification of an evolutionary conserved structural loop that is required for the enzymatic and biological function of tryptophan 2,3-dioxygenase.
Michels, Helen; Seinstra, Renée I; Uitdehaag, Joost C M; Koopman, Mandy; van Faassen, Martijn; Martineau, Céline N; Kema, Ido P; Buijsman, Rogier; Nollen, Ellen A A.
Afiliación
  • Michels H; European Research Institute for the Biology of Aging, University of Groningen, University Medical Center Groningen, Laboratory of Molecular Neurobiology of Aging, The Netherlands.
  • Seinstra RI; European Research Institute for the Biology of Aging, University of Groningen, University Medical Center Groningen, Laboratory of Molecular Neurobiology of Aging, The Netherlands.
  • Uitdehaag JC; Netherlands Translational Research Center B.V., Oss, The Netherlands.
  • Koopman M; European Research Institute for the Biology of Aging, University of Groningen, University Medical Center Groningen, Laboratory of Molecular Neurobiology of Aging, The Netherlands.
  • van Faassen M; University of Groningen, University Medical Center Groningen, Department of Laboratory Medicine, The Netherlands.
  • Martineau CN; European Research Institute for the Biology of Aging, University of Groningen, University Medical Center Groningen, Laboratory of Molecular Neurobiology of Aging, The Netherlands.
  • Kema IP; University of Groningen, University Medical Center Groningen, Department of Laboratory Medicine, The Netherlands.
  • Buijsman R; Netherlands Translational Research Center B.V., Oss, The Netherlands.
  • Nollen EA; European Research Institute for the Biology of Aging, University of Groningen, University Medical Center Groningen, Laboratory of Molecular Neurobiology of Aging, The Netherlands.
Sci Rep ; 6: 39199, 2016 12 20.
Article en En | MEDLINE | ID: mdl-27995966

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triptófano Oxigenasa / Caenorhabditis elegans / Evolución Molecular / Proteínas de Caenorhabditis elegans Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triptófano Oxigenasa / Caenorhabditis elegans / Evolución Molecular / Proteínas de Caenorhabditis elegans Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido