[An aid to the electrophysiological diagnosis of diabetic peripheral neuropathy]. / Aide au diagnostic électrophysiologique de la neuropathie périphérique diabétique.
Neurophysiol Clin
; 19(4): 327-37, 1989 Aug.
Article
en Fr
| MEDLINE
| ID: mdl-2796928
The electrophysiological diagnosis of peripheral neuropathy in diabetics becomes increasingly difficult with the increase in number of parameters measured. We have examined 102 subjects: 60 diabetics, 32 control subjects and 10 with impaired glucose tolerance. From the 37 recorded parameters during 8 examinations, a linear discriminant analysis allowed us to separate the 19 diabetics with clinical neuropathy and the control subjects with only 5 parameters, with a good concordance (96%): the motor conduction velocities (MCV) of the peroneal and median nerves, the amplitude of the action potential (AP) of the sural nerve, the Hmax/Mmax ratio and the M latency of the Hoffman reflex. These parameters, weighted with a coefficient, constitute a score of discrimination. This score has been tested by the Jackknife method on the same sample (94% of well-classified patients), then validated on the other patients. Thus we propose a method to aid the diagnosis of diabetic peripheral neuropathy, without the arbitrary character of the classical single parameter method, and allowing easy repetition.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Diabetes Mellitus Tipo 1
/
Diabetes Mellitus Tipo 2
/
Neuropatías Diabéticas
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Fr
Revista:
Neurophysiol Clin
Asunto de la revista:
FISIOLOGIA
/
NEUROLOGIA
Año:
1989
Tipo del documento:
Article
País de afiliación:
Francia
Pais de publicación:
Francia