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ß-Amyrin synthase from Euphorbia tirucalli L. functional analyses of the highly conserved aromatic residues Phe413, Tyr259 and Trp257 disclose the importance of the appropriate steric bulk, and cation-π and CH-π interactions for the efficient catalytic action of the polyolefin cyclization cascade.
Ito, Ryousuke; Nakada, Chika; Hoshino, Tsutomu.
Afiliación
  • Ito R; Graduate School of Science and Technology and Department of Applied Biological Chemistry, Faculty of Agriculture, Niigata University, Ikarashi 2-8050, Nishi-ku, Niigata 950-2181, Japan. hoshitsu@agr.niigata-u.ac.jp.
  • Nakada C; Graduate School of Science and Technology and Department of Applied Biological Chemistry, Faculty of Agriculture, Niigata University, Ikarashi 2-8050, Nishi-ku, Niigata 950-2181, Japan. hoshitsu@agr.niigata-u.ac.jp.
  • Hoshino T; Graduate School of Science and Technology and Department of Applied Biological Chemistry, Faculty of Agriculture, Niigata University, Ikarashi 2-8050, Nishi-ku, Niigata 950-2181, Japan. hoshitsu@agr.niigata-u.ac.jp.
Org Biomol Chem ; 15(1): 177-188, 2016 12 20.
Article en En | MEDLINE | ID: mdl-27942657
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Oleanólico / Polienos / Transferasas Intramoleculares / Euphorbia Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Buscar en Google
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Oleanólico / Polienos / Transferasas Intramoleculares / Euphorbia Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido