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Effect of diabetes mellitus on the clinical outcome of lower limb arterial bypass surgery: A propensity score analysis.
Lazaris, Andreas M; Kontopantelis, Evangelos; Antonopoulos, Konstantinos; Mantas, Georgios; Kouvelos, Georgios; Moulakakis, Konstantinos; Matsagkas, Miltiadis I; Vasdekis, Spyros N; Geroulakos, George.
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  • Lazaris AM; 1 Vascular Surgery Department, School of Medicine, National and Kapodistrian University of Athens, Attikon Teaching Hospital, Athens, Greece.
  • Kontopantelis E; 2 Faculty of Medicine, University of Manchester, Manchester, UK.
  • Antonopoulos K; 1 Vascular Surgery Department, School of Medicine, National and Kapodistrian University of Athens, Attikon Teaching Hospital, Athens, Greece.
  • Mantas G; 1 Vascular Surgery Department, School of Medicine, National and Kapodistrian University of Athens, Attikon Teaching Hospital, Athens, Greece.
  • Kouvelos G; 3 Department of Surgery, Vascular Surgery Unit, Medical School, University of Ioannina, Ioannina, Greece.
  • Moulakakis K; 1 Vascular Surgery Department, School of Medicine, National and Kapodistrian University of Athens, Attikon Teaching Hospital, Athens, Greece.
  • Matsagkas MI; 3 Department of Surgery, Vascular Surgery Unit, Medical School, University of Ioannina, Ioannina, Greece.
  • Vasdekis SN; 1 Vascular Surgery Department, School of Medicine, National and Kapodistrian University of Athens, Attikon Teaching Hospital, Athens, Greece.
  • Geroulakos G; 1 Vascular Surgery Department, School of Medicine, National and Kapodistrian University of Athens, Attikon Teaching Hospital, Athens, Greece.
Vascular ; 25(4): 364-371, 2017 Aug.
Article en En | MEDLINE | ID: mdl-27940896
Objectives Diabetic patients who undergo lower limb arterial bypass surgery are considered to have a worse clinical outcome compared to non-diabetics. The aim of the study was to test this hypothesis after applying propensity score matching analysis. Patients and methods A total of 113 consecutive lower limb bypass procedures (55 diabetic and 58 non-diabetic) were evaluated regarding their clinical outcome. Endpoints of the study included amputation-free survival, limb salvage, patency and patients' survival up to 36 months post-procedure. After propensity score matching analysis, two new groups, diabetic and non-diabetic, of 31 limbs in each one were created, both equivalent regarding all baseline characteristics. Results Between the propensity score matching groups, the amputation-free survival was 68.8% in the non-diabetic and 37.7% in the diabetic group at 36 months ( p = 0.004). Similarly, the survival was 88.6% and 57.6%, respectively, in the two groups at the same time point ( p = 0.01). On the contrary, no difference was found in patency (58.3% vs. 56%) and in limb salvage rate (74.1% vs. 60.8%). Conclusions Lower limbs arterial bypass surgery has similar results regarding patency and limb salvage rate in diabetic and non-diabetic patients. On the contrary, mortality is worse in diabetic patients, this affecting negatively their amputation-free survival.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procedimientos Quirúrgicos Vasculares / Extremidad Inferior / Angiopatías Diabéticas / Enfermedad Arterial Periférica Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Vascular Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procedimientos Quirúrgicos Vasculares / Extremidad Inferior / Angiopatías Diabéticas / Enfermedad Arterial Periférica Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Vascular Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido