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Successful Cord Blood Stem Cell Transplantation for an Adult Case of Chronic Active Epstein-Barr Virus Infection.
Saburi, Masuho; Ogata, Masao; Satou, Takako; Yoshida, Natsumi; Nagamatsu, Kentaro; Nashimoto, Yuko; Moroga, Yui; Takano, Kuniko; Kohno, Kazuhiro; Shirao, Kuniaki.
Afiliación
  • Saburi M; Department of Medical Oncology and Hematology, Oita University Faculty of Medicine, Japan.
Intern Med ; 55(23): 3499-3504, 2016.
Article en En | MEDLINE | ID: mdl-27904117
A 41-year-old man was referred to our hospital for treatment of anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma. Chronic active Epstein-Barr virus (CAEBV) was diagnosed based on the findings of elevated EBV antibody titers and positive EBV-DNA in the peripheral blood, and cord blood stem cell transplantation (CBT) was performed. The EBV-DNA levels in the blood fell below the limit of detection. His lymphoma relapsed on Day 165 with the appearance of eruptions, which disappeared after the withdrawal of tacrolimus. One year after transplantation, there were no signs of recurrence. This encouraging result suggests that CBT should be considered for adult cases of CAEBV with aggressive clinical manifestations.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Herpesvirus Humano 4 / Infecciones por Virus de Epstein-Barr / Trasplante de Células Madre de Sangre del Cordón Umbilical Tipo de estudio: Diagnostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2016 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Herpesvirus Humano 4 / Infecciones por Virus de Epstein-Barr / Trasplante de Células Madre de Sangre del Cordón Umbilical Tipo de estudio: Diagnostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2016 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón