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Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic ß-cells.
Brereton, Melissa F; Rohm, Maria; Shimomura, Kenju; Holland, Christian; Tornovsky-Babeay, Sharona; Dadon, Daniela; Iberl, Michaela; Chibalina, Margarita V; Lee, Sheena; Glaser, Benjamin; Dor, Yuval; Rorsman, Patrik; Clark, Anne; Ashcroft, Frances M.
Afiliación
  • Brereton MF; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford OX1 3PT, UK.
  • Rohm M; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford OX1 3PT, UK.
  • Shimomura K; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford OX1 3PT, UK.
  • Holland C; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford OX1 3PT, UK.
  • Tornovsky-Babeay S; Endocrinology and Metabolism Service, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel.
  • Dadon D; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
  • Iberl M; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford OX1 3PT, UK.
  • Chibalina MV; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.
  • Lee S; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford OX1 3PT, UK.
  • Glaser B; Endocrinology and Metabolism Service, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel.
  • Dor Y; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
  • Rorsman P; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.
  • Clark A; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.
  • Ashcroft FM; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford OX1 3PT, UK.
Nat Commun ; 7: 13496, 2016 11 24.
Article en En | MEDLINE | ID: mdl-27882918

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glucemia / Apoptosis / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Glucógeno / Hiperglucemia / Enfermedades del Recién Nacido Límite: Animals / Humans / Newborn Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glucemia / Apoptosis / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Glucógeno / Hiperglucemia / Enfermedades del Recién Nacido Límite: Animals / Humans / Newborn Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido