Biosynthesis of the psychotropic plant diterpene salvinorin A: Discovery and characterization of the Salvia divinorum clerodienyl diphosphate synthase.

Pelot, Kyle A; Mitchell, Rod; Kwon, Moonhyuk; Hagelthorn, Lynne M; Wardman, Jacob F; Chiang, Angela; Bohlmann, Jörg; Ro, Dae-Kyun; Zerbe, Philipp

Pelot, Kyle A; Mitchell, Rod; Kwon, Moonhyuk; Hagelthorn, Lynne M; Wardman, Jacob F; Chiang, Angela; Bohlmann, Jörg; Ro, Dae-Kyun; Zerbe, Philipp.

Afiliación

Pelot KA; Department of Plant Biology, University of California-Davis, 1 Shields Avenue, Davis, CA, 95616, USA.
Mitchell R; Department of Biological Sciences, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N1N4, Canada.
Kwon M; Department of Biological Sciences, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N1N4, Canada.
Hagelthorn LM; Department of Plant Biology, University of California-Davis, 1 Shields Avenue, Davis, CA, 95616, USA.
Wardman JF; Department of Biological Sciences, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N1N4, Canada.
Chiang A; Michael Smith Laboratories, University of British Columbia, 2185 East Mall, Vancouver, BC, V6T 1Z4, Canada.
Bohlmann J; Michael Smith Laboratories, University of British Columbia, 2185 East Mall, Vancouver, BC, V6T 1Z4, Canada.
Ro DK; Department of Biological Sciences, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N1N4, Canada.
Zerbe P; Department of Plant Biology, University of California-Davis, 1 Shields Avenue, Davis, CA, 95616, USA.

Plant J ; 89(5): 885-897, 2017 03.

Article en En | MEDLINE | ID: mdl-27865008

Asunto(s)

Transferasas Alquil y Aril/metabolismo; Diterpenos de Tipo Clerodano/metabolismo; Diterpenos/metabolismo; Proteínas de Plantas/metabolismo; Salvia/enzimología; Salvia/metabolismo; Transferasas Alquil y Aril/genética; Productos Biológicos/metabolismo; Proteínas de Plantas/genética; Salvia/genética

Palabras clave

Salvia divinorum; botanicals; diterpene synthases; diterpenoid metabolism; pathway discovery; plant natural product; salvinorin A

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Plantas / Transferasas Alquil y Aril / Salvia / Diterpenos de Tipo Clerodano / Diterpenos Idioma: En Revista: Plant J Asunto de la revista: BIOLOGIA MOLECULAR / BOTANICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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