Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation.

Mancini, Sarah J; White, Anna D; Bijland, Silvia; Rutherford, Claire; Graham, Delyth; Richter, Erik A; Viollet, Benoit; Touyz, Rhian M; Palmer, Timothy M; Salt, Ian P

Mancini, Sarah J; White, Anna D; Bijland, Silvia; Rutherford, Claire; Graham, Delyth; Richter, Erik A; Viollet, Benoit; Touyz, Rhian M; Palmer, Timothy M; Salt, Ian P.

Afiliación

Mancini SJ; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
White AD; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
Bijland S; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
Rutherford C; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
Graham D; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
Richter EA; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Denmark.
Viollet B; INSERM, U1016, Institut Cochin, Paris, France; CNRS, UMR8104, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, France.
Touyz RM; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
Palmer TM; School of Pharmacy, University of Bradford, Bradford, West Yorkshire, BD7 1DP, United Kingdom.
Salt IP; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom. Electronic address: Ian.Salt@glasgow.ac.uk.

Mol Cell Endocrinol ; 440: 44-56, 2017 01 15.

Article en En | MEDLINE | ID: mdl-27840174

Asunto(s)

Proteínas Quinasas Activadas por AMP/metabolismo; Adipocitos/enzimología; Adipocitos/patología; Inflamación/enzimología; Inflamación/patología; Quinasas Asociadas a Receptores de Interleucina-1/metabolismo; Células 3T3-L1; Adipogénesis/efectos de los fármacos; Animales; Compuestos de Bifenilo; Quimiocina CXCL10/genética; Quimiocina CXCL10/metabolismo; Activación Enzimática/efectos de los fármacos; Femenino; Humanos; Interleucina-1beta/metabolismo; Interleucina-6/metabolismo; Ratones; FN-kappa B/metabolismo; Fosforilación/efectos de los fármacos; Pironas/farmacología; ARN Mensajero/genética; ARN Mensajero/metabolismo; Receptores de Interleucina-6/metabolismo; Factor de Transcripción STAT3/metabolismo; Tiofenos/farmacología

Palabras clave

AMP-activated protein kinase; Adipocyte; Inflammation; Signalling

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adipocitos / Quinasas Asociadas a Receptores de Interleucina-1 / Proteínas Quinasas Activadas por AMP / Inflamación Tipo de estudio: Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: Mol Cell Endocrinol Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Irlanda

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