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Pathophysiological and clinical aspects of gastric hyperplastic polyps.
Markowski, Adam Roman; Markowska, Agnieszka; Guzinska-Ustymowicz, Katarzyna.
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  • Markowski AR; Adam Roman Markowski, Department of Internal Medicine and Gastroenterology, Polish Red Cross Memorial Municipal Hospital, 15-003 Bialystok, Poland.
  • Markowska A; Adam Roman Markowski, Department of Internal Medicine and Gastroenterology, Polish Red Cross Memorial Municipal Hospital, 15-003 Bialystok, Poland.
  • Guzinska-Ustymowicz K; Adam Roman Markowski, Department of Internal Medicine and Gastroenterology, Polish Red Cross Memorial Municipal Hospital, 15-003 Bialystok, Poland.
World J Gastroenterol ; 22(40): 8883-8891, 2016 Oct 28.
Article en En | MEDLINE | ID: mdl-27833379
Gastric polyps become a major clinical problem because of high prevalence and tendency to malignant transformation of some of them. The development of gastric hyperplastic polyps results from excessive proliferation of foveolar cells accompanied by their increased exfoliation, and they are macroscopically indistinguishable from other polyps with lower or higher malignant potential. Panendoscopy allows detection and differentiation of gastric polyps, usually after obtaining histopathological biopsy specimens. Unremoved gastric hyperplastic polyps may enlarge and sometimes spontaneously undergo a sequential progression to cancer. For this reason, gastric hyperplastic polyps larger than 5 mm in size should be removed in one piece. After excision of polyps with atypical focal lesion, endoscopic surveillance is suggested depending on histopathological diagnosis and possibility of confirming the completeness of endoscopic resection. Because of the risk of cancer development also in gastric mucosa outside the polyp, neighboring fragments of gastric mucosa should undergo microscopic investigations. This procedure allows for identification of patients who can benefit most from oncological endoscopic surveillance. If Helicobacter pylori (H. pylori) infection of the gastric mucosa is confirmed, treatment strategies should include eradication of bacteria, which may prevent progression of intestinal metaplasia. The efficacy of H. pylori eradication should be checked 3-6 mo later.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pólipos / Estómago / Gastropatías / Carcinoma in Situ Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: World J Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pólipos / Estómago / Gastropatías / Carcinoma in Situ Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: World J Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Estados Unidos