Transcriptome and Proteome Analyses of TNFAIP8 Knockdown Cancer Cells Reveal New Insights into Molecular Determinants of Cell Survival and Tumor Progression.

Day, Timothy F; Mewani, Rajshree R; Starr, Joshua; Li, Xin; Chakravarty, Debyani; Ressom, Habtom; Zou, Xiaojun; Eidelman, Ofer; Pollard, Harvey B; Srivastava, Meera; Kasid, Usha N

Day, Timothy F; Mewani, Rajshree R; Starr, Joshua; Li, Xin; Chakravarty, Debyani; Ressom, Habtom; Zou, Xiaojun; Eidelman, Ofer; Pollard, Harvey B; Srivastava, Meera; Kasid, Usha N.

Afiliación

Day TF; Georgetown-Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Rd, NW, Washington, DC, 20057, USA.
Mewani RR; Georgetown-Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Rd, NW, Washington, DC, 20057, USA.
Starr J; Department of Anatomy, Physiology and Genetics, Institute for Molecular Medicine, Center for Medical Proteomics, Uniformed Services University School of Medicine, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Li X; Georgetown-Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Rd, NW, Washington, DC, 20057, USA.
Chakravarty D; Georgetown-Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Rd, NW, Washington, DC, 20057, USA.
Ressom H; Georgetown-Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Rd, NW, Washington, DC, 20057, USA.
Zou X; Georgetown-Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Rd, NW, Washington, DC, 20057, USA.
Eidelman O; Department of Anatomy, Physiology and Genetics, Institute for Molecular Medicine, Center for Medical Proteomics, Uniformed Services University School of Medicine, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Pollard HB; Department of Anatomy, Physiology and Genetics, Institute for Molecular Medicine, Center for Medical Proteomics, Uniformed Services University School of Medicine, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Srivastava M; Department of Anatomy, Physiology and Genetics, Institute for Molecular Medicine, Center for Medical Proteomics, Uniformed Services University School of Medicine, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Kasid UN; Georgetown-Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Rd, NW, Washington, DC, 20057, USA. kasidu@georgetown.edu.

Methods Mol Biol ; 1513: 83-100, 2017.

Article en En | MEDLINE | ID: mdl-27807832

Asunto(s)

Proteínas Reguladoras de la Apoptosis/genética; Neoplasias de la Mama/genética; Regulación Neoplásica de la Expresión Génica; Melanoma/genética; Neoplasias de la Próstata/genética; Proteómica/métodos; Secuencia de Aminoácidos; Proteínas Reguladoras de la Apoptosis/antagonistas & inhibidores; Proteínas Reguladoras de la Apoptosis/metabolismo; Neoplasias de la Mama/diagnóstico; Neoplasias de la Mama/metabolismo; Neoplasias de la Mama/patología; Supervivencia Celular; Progresión de la Enfermedad; Transportador 3 de Aminoácidos Excitadores/genética; Transportador 3 de Aminoácidos Excitadores/metabolismo; Femenino; Humanos; Masculino; Melanoma/diagnóstico; Melanoma/metabolismo; Melanoma/patología; FN-kappa B/genética; FN-kappa B/metabolismo; Proteínas Oncogénicas/genética; Proteínas Oncogénicas/metabolismo; Pronóstico; Neoplasias de la Próstata/diagnóstico; Neoplasias de la Próstata/metabolismo; Neoplasias de la Próstata/patología; ARN Interferente Pequeño/genética; ARN Interferente Pequeño/metabolismo; Transducción de Señal

Palabras clave

Antibody arrays; Cancer systems biology; Cell survival and proliferation; Invasion and metastasis; RNA and microRNA arrays; TNFAIP8; shRNA and siRNA

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Neoplasias de la Mama / Regulación Neoplásica de la Expresión Génica / Proteómica / Proteínas Reguladoras de la Apoptosis / Melanoma Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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