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Isolation of Coronavirus NL63 from Blood from Children in Rural Haiti: Phylogenetic Similarities with Recent Isolates from Malaysia.
Beau De Rochars, Valery Madsen; Lednicky, John; White, Sarah; Loeb, Julia; Elbadry, Maha A; Telisma, Taina; Chavannes, Sonese; Anilis, Marie Gina; Cella, Eleonora; Ciccozzi, Massimo; Okech, Bernard A; Salemi, Marco; Morris, J Glenn.
Afiliación
  • Beau De Rochars VM; Emerging Pathogens Institute, University of Florida, Gainesville, Florida.
  • Lednicky J; Department of Health Services Research, Management and Policy, College of Public Health and Health Professions, University of Florida, Gainesville, Florida.
  • White S; Emerging Pathogens Institute, University of Florida, Gainesville, Florida.
  • Loeb J; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, Florida.
  • Elbadry MA; Emerging Pathogens Institute, University of Florida, Gainesville, Florida.
  • Telisma T; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, Florida.
  • Chavannes S; Emerging Pathogens Institute, University of Florida, Gainesville, Florida.
  • Anilis MG; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, Florida.
  • Cella E; Emerging Pathogens Institute, University of Florida, Gainesville, Florida.
  • Ciccozzi M; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, Florida.
  • Okech BA; Emerging Pathogens Institute, University of Florida, Gainesville, Florida.
  • Salemi M; Christianville Foundation, School Clinic, Gressier, Haiti.
  • Morris JG; Emerging Pathogens Institute, University of Florida, Gainesville, Florida.
Am J Trop Med Hyg ; 96(1): 144-147, 2017 Jan 11.
Article en En | MEDLINE | ID: mdl-27799635
Human coronavirus (HCoV) NL63 is recognized as a common cause of upper respiratory infections and influenza-like illness. In screening children with acute undifferentiated febrile illness in a school cohort in rural Haiti, we identified HCoV-NL63 in blood samples from four children. Cases clustered over an 11-day period; children did not have respiratory symptoms, but two had gastrointestinal complaints. On phylogenetic analysis, the Haitian HCoV-NL63 strains cluster together in a highly supported monophyletic clade linked most closely with recently reported strains from Malaysia; two respiratory HCoV-NL63 strains identified in north Florida in the same general period form a separate clade, albeit again with close linkages with the Malaysian strains. Our data highlight the variety of presentations that may be seen with HCoV-NL63, and underscore the apparent ease with which CoV strains move among countries, with our data consistent with recurrent introduction of strains into the Caribbean (Haiti and Florida) from Asia.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Coronavirus / Coronavirus Límite: Child / Female / Humans / Male País/Región como asunto: Asia / Caribe / Haiti Idioma: En Revista: Am J Trop Med Hyg Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Coronavirus / Coronavirus Límite: Child / Female / Humans / Male País/Región como asunto: Asia / Caribe / Haiti Idioma: En Revista: Am J Trop Med Hyg Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos