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Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis.
Verma, Nandini; Müller, Anna-Katharina; Kothari, Charu; Panayotopoulou, Effrosini; Kedan, Amir; Selitrennik, Michael; Mills, Gordon B; Nguyen, Lan K; Shin, Sungyoung; Karn, Thomas; Holtrich, Uwe; Lev, Sima.
Afiliación
  • Verma N; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Müller AK; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Kothari C; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Panayotopoulou E; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Kedan A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Selitrennik M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Mills GB; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Nguyen LK; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Australia.
  • Shin S; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Australia.
  • Karn T; Department of Obstetrics and Gynecology, Goethe University Frankfurt, Frankfurt, Germany.
  • Holtrich U; Department of Obstetrics and Gynecology, Goethe University Frankfurt, Frankfurt, Germany.
  • Lev S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel. sima.lev@weizmann.ac.il.
Cancer Res ; 77(1): 86-99, 2017 01 01.
Article en En | MEDLINE | ID: mdl-27793840
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Resistencia a Antineoplásicos / Quinasa 2 de Adhesión Focal / Neoplasias de la Mama Triple Negativas / Receptores ErbB Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2017 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Resistencia a Antineoplásicos / Quinasa 2 de Adhesión Focal / Neoplasias de la Mama Triple Negativas / Receptores ErbB Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2017 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Estados Unidos