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Antibacterial activity of Pyrrosia petiolosa ethyl acetate extract against Staphylococcus aureus by decreasing hla and sea virulence genes.
Song, Liju; Cao, Mei; Chen, Chong; Qi, Panpan; Li, Ningzhe; Wu, Daoyan; Peng, Jingshan; Wang, Xuege; Zhang, Mao; Hu, Guoku; Zhao, Jian.
Afiliación
  • Song L; a Key Laboratory of Biological Resource and Ecological Environment of Chinese Education Ministry , College of Life Sciences, Sichuan University , Chengdu , P.R. China.
  • Cao M; b Core Laboratory , School of Medicine, Sichuan Provincial People's Hospital Affiliated to University of Electronic Science and Technology of China , Chengdu , P.R. China.
  • Chen C; a Key Laboratory of Biological Resource and Ecological Environment of Chinese Education Ministry , College of Life Sciences, Sichuan University , Chengdu , P.R. China.
  • Qi P; a Key Laboratory of Biological Resource and Ecological Environment of Chinese Education Ministry , College of Life Sciences, Sichuan University , Chengdu , P.R. China.
  • Li N; a Key Laboratory of Biological Resource and Ecological Environment of Chinese Education Ministry , College of Life Sciences, Sichuan University , Chengdu , P.R. China.
  • Wu D; a Key Laboratory of Biological Resource and Ecological Environment of Chinese Education Ministry , College of Life Sciences, Sichuan University , Chengdu , P.R. China.
  • Peng J; a Key Laboratory of Biological Resource and Ecological Environment of Chinese Education Ministry , College of Life Sciences, Sichuan University , Chengdu , P.R. China.
  • Wang X; a Key Laboratory of Biological Resource and Ecological Environment of Chinese Education Ministry , College of Life Sciences, Sichuan University , Chengdu , P.R. China.
  • Zhang M; b Core Laboratory , School of Medicine, Sichuan Provincial People's Hospital Affiliated to University of Electronic Science and Technology of China , Chengdu , P.R. China.
  • Hu G; b Core Laboratory , School of Medicine, Sichuan Provincial People's Hospital Affiliated to University of Electronic Science and Technology of China , Chengdu , P.R. China.
  • Zhao J; c Department of Pharmacology and Experimental Neuroscience , University of Nebraska Medical Center , Omaha , NE , USA.
Nat Prod Res ; 31(11): 1347-1350, 2017 Jun.
Article en En | MEDLINE | ID: mdl-27784177
The aim of this study was to explore the antibacterial activity of Pyrrosia petiolosa ethyl acetate extract (PPEAE) against Staphylococcus aureus in vitro and analyse its chemical components by gas chromatograph-mass spectrometry. The results of anti-microbial assay revealed that PPEAE had strong inhibitory activity against S .aureus, with MIC and MBC of 7.8 and 15.6 mg/mL, respectively. The transcriptional levels of hla and sea were reduced to 14.33 and 46.39% at the MIC compared to the control. Analysing test result exhibited that eugenol made a great contribution to antibacterial activity. This experiment indicated that PPEAE had prominent antibacterial activity against S. aureus.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Staphylococcus aureus / Virulencia / Extractos Vegetales / Polypodiaceae / Antibacterianos Idioma: En Revista: Nat Prod Res Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Staphylococcus aureus / Virulencia / Extractos Vegetales / Polypodiaceae / Antibacterianos Idioma: En Revista: Nat Prod Res Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido