Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.

Majorek, Karolina A; Osinski, Tomasz; Tran, David T; Revilla, Alina; Anderson, Wayne F; Minor, Wladek; Kuhn, Misty L

Majorek, Karolina A; Osinski, Tomasz; Tran, David T; Revilla, Alina; Anderson, Wayne F; Minor, Wladek; Kuhn, Misty L.

Afiliación

Majorek KA; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22908, USA; Center for Structural Genomics of Infectious Diseases (CSGID).
Osinski T; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22908, USA; Center for Structural Genomics of Infectious Diseases (CSGID).
Tran DT; Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132, USA.
Revilla A; Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132, USA.
Anderson WF; Northwestern University Feinberg School of Medicine, Department of Molecular Pharmacology and Biological Chemistry, Chicago, IL 60611, USA; Center for Structural Genomics of Infectious Diseases (CSGID).
Minor W; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22908, USA; Center for Structural Genomics of Infectious Diseases (CSGID). Electronic address: wladek@iwonka.med.virginia.edu.
Kuhn ML; Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132, USA. Electronic address: mkuhn@sfsu.edu.

Biochim Biophys Acta Proteins Proteom ; 1865(1): 55-64, 2017 Jan.

Article en En | MEDLINE | ID: mdl-27783928

Asunto(s)

Acetiltransferasas/metabolismo; Clostridioides difficile/enzimología; Staphylococcus aureus/enzimología; Acetiltransferasas/química; Secuencia de Aminoácidos; Mutagénesis Sitio-Dirigida; Conformación Proteica; Homología de Secuencia de Aminoácido; Especificidad por Sustrato

Palabras clave

Acetyltransferase; Amino acid acetylation; GNAT; Gcn5-related N-acetyltransferase; Serine and threonine acetylation

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetiltransferasas / Staphylococcus aureus / Clostridioides difficile Idioma: En Revista: Biochim Biophys Acta Proteins Proteom Año: 2017 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google