Your browser doesn't support javascript.
loading
Worldwide Esophageal Cancer Collaboration: pathologic staging data.
Rice, T W; Chen, L-Q; Hofstetter, W L; Smithers, B M; Rusch, V W; Wijnhoven, B P L; Chen, K L; Davies, A R; D'Journo, X B; Kesler, K A; Luketich, J D; Ferguson, M K; Räsänen, J V; van Hillegersberg, R; Fang, W; Durand, L; Cecconello, I; Allum, W H; Cerfolio, R J; Pera, M; Griffin, S M; Burger, R; Liu, J-F; Allen, M S; Law, S; Watson, T J; Darling, G E; Scott, W J; Duranceau, A; Denlinger, C E; Schipper, P H; Lerut, T E M R; Orringer, M B; Ishwaran, H; Apperson-Hansen, C; DiPaola, L M; Semple, M E; Blackstone, E H.
Afiliación
  • Rice TW; Cleveland Clinic, Cleveland, Ohio, USA. ricet@ccf.org.
  • Chen LQ; West China Hospital of Sichuan University, Chengdu, Sichuan, China.
  • Hofstetter WL; University of Texas MD Anderson Hospital, Houston, Texas, USA.
  • Smithers BM; University of Queensland, Princess Alexandra Hospital, Brisbane, Australia.
  • Rusch VW; Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Wijnhoven BP; Erasmus Medical Center, Rotterdam, The Netherlands.
  • Chen KL; Beijing Cancer Hospital, Beijing, China.
  • Davies AR; Guy's & St Thomas' Hospitals, London, England.
  • D'Journo XB; Hôpital Nord, Marseille, France.
  • Kesler KA; Indiana University Medical Center, Indianapolis, Indiana, USA.
  • Luketich JD; University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
  • Ferguson MK; Department of Surgery, The University of Chicago, Chicago, Illinois, USA.
  • Räsänen JV; Helsinki University Hospital, Helsinki, Finland.
  • van Hillegersberg R; University Medical Center Utrecht, Utrecht, The Netherlands.
  • Fang W; Shanghai Chest Hospital, Shanghai, China.
  • Durand L; Hospital de Clinicas, University of Buenos Aires, Buenos Aires, Argentina.
  • Cecconello I; University of São Paulo School of Medicine, São Paulo, Brazil.
  • Allum WH; Royal Marsden NHS Foundation Trust, London, UK.
  • Cerfolio RJ; Section of Thoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  • Pera M; Hospital Universitario del Mar, Barcelona, Spain.
  • Griffin SM; University of Newcastle upon Tyne, Newcastle, United Kingdom.
  • Burger R; University of Cape Town, Groote Schuur Hospital, Cape Town, South Africa.
  • Liu JF; Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
  • Allen MS; Mayo Clinic, Rochester, Minnesota, USA.
  • Law S; University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong, China.
  • Watson TJ; University of Rochester, Rochester, New York, USA.
  • Darling GE; Toronto General Hospital, Toronto, Ontario, Canada.
  • Scott WJ; Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
  • Duranceau A; University of Montreal, Montreal, Quebec, Canada.
  • Denlinger CE; Medical University of South Carolina, Charleston, South Carolina, USA.
  • Schipper PH; Oregon Health & Science University, Portland, Oregon, USA.
  • Lerut TE; University Ziekenhuizen Leuven, Leuven, Belgium.
  • Orringer MB; University of Michigan, Ann Arbor, Michigan, USA.
  • Ishwaran H; University of Miami, Miami, Florida, USA.
  • Apperson-Hansen C; Case Western Reserve University, Cleveland, Ohio, USA.
  • DiPaola LM; Cleveland Clinic, Cleveland, Ohio, USA.
  • Semple ME; Cleveland Clinic, Cleveland, Ohio, USA.
  • Blackstone EH; Cleveland Clinic, Cleveland, Ohio, USA.
Dis Esophagus ; 29(7): 724-733, 2016 Oct.
Article en En | MEDLINE | ID: mdl-27731547
We report data-simple descriptions of patient characteristics, cancer categories, and non-risk-adjusted survival-for patients with pathologically staged cancer of the esophagus and esophagogastric junction after resection or ablation with no preoperative therapy from the Worldwide Esophageal Cancer Collaboration (WECC). Thirty-three institutions from six continents submitted de-identified data using standard definitions: demographics, comorbidities, clinical cancer categories, and all-cause mortality from first management decision. Of 13,300 patients, 5,631 had squamous cell carcinoma, 7,558 adenocarcinoma, 85 adenosquamous carcinoma, and 26 undifferentiated carcinoma. Patients were older (62 years) men (80%) with normal body mass index (51%), little weight loss (1.8 kg), 0-2 ECOG performance status (83%), and a history of smoking (70%). Cancers were pT1 (24%), pT2 (15%), pT3 (50%), pN0 (52%), pM0 (93%), and pG2-G3 (78%); most involved distal esophagus (71%). Non-risk-adjusted survival for both squamous cell carcinoma and adenocarcinoma was monotonic and distinctive across pTNM. Survival was more distinctive for adenocarcinoma than squamous cell carcinoma when pT was ordered by pN. Survival for pTis-1 adenocarcinoma was better than for squamous cell carcinoma, although monotonic and distinctive for both. WECC pathologic staging data is improved over that of the 7th edition, with more patients studied and patient and cancer variables collected. These data will be the basis for the 8th edition cancer staging manuals following risk adjustment for patient, cancer, and treatment characteristics, and should direct 9th edition data collection. However, the role of pure pathologic staging as the principal point of reference for esophageal cancer staging is waning.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Carcinoma / Esofagectomía / Técnicas de Ablación / Estadificación de Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Dis Esophagus Asunto de la revista: GASTROENTEROLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Carcinoma / Esofagectomía / Técnicas de Ablación / Estadificación de Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Dis Esophagus Asunto de la revista: GASTROENTEROLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos