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Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites.
Wang, Mingping; Tian, Wei; Wang, Chongqing; Lu, Shihai; Yang, Chao; Wang, Juan; Song, Yunlong; Zhou, Youjun; Zhu, Ju; Li, Zhiyu; Zheng, Canhui.
Afiliación
  • Wang M; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China; School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
  • Tian W; School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
  • Wang C; School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
  • Lu S; School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
  • Yang C; School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
  • Wang J; Shanghai Institute of Pharmaceutical Industry, Shanghai 200437, China.
  • Song Y; School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
  • Zhou Y; School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
  • Zhu J; School of Pharmacy, Second Military Medical University, Shanghai 200433, China. Electronic address: zhuju@smmu.edu.cn.
  • Li Z; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China. Electronic address: zhiyuli@cpu.edu.cn.
  • Zheng C; School of Pharmacy, Second Military Medical University, Shanghai 200433, China. Electronic address: canhuizheng@smmu.edu.cn.
Bioorg Med Chem Lett ; 26(21): 5207-5211, 2016 11 01.
Article en En | MEDLINE | ID: mdl-27712939
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apoptosis / Proteínas Proto-Oncogénicas c-bcl-2 Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apoptosis / Proteínas Proto-Oncogénicas c-bcl-2 Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido