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Regulating Stem Cell Secretome Using Injectable Hydrogels with In Situ Network Formation.
Cai, Lei; Dewi, Ruby E; Goldstone, Andrew B; Cohen, Jeffrey E; Steele, Amanda N; Woo, Y Joseph; Heilshorn, Sarah C.
Afiliación
  • Cai L; Department of Materials Science and Engineering, Stanford Neuroscience Institute, Stanford University, Stanford, CA, 94305, USA.
  • Dewi RE; Department of Materials Science and Engineering, Stanford University, Stanford, CA, 94305, USA.
  • Goldstone AB; Department of Cardiothoracic Surgery, Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.
  • Cohen JE; Department of Cardiothoracic Surgery, Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.
  • Steele AN; Department of Cardiothoracic Surgery, Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.
  • Woo YJ; Department of Cardiothoracic Surgery, Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.
  • Heilshorn SC; Department of Materials Science and Engineering, Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.
Adv Healthc Mater ; 5(21): 2758-2764, 2016 11.
Article en En | MEDLINE | ID: mdl-27709809
A family of shear-thinning hydrogels for injectable encapsulation and long-term delivery (SHIELD) has been designed and synthesized with controlled in situ stiffening properties to regulate the stem cell secretome. The authors demonstrate that SHIELD with an intermediate stiffness (200-400 Pa) could significantly promote the angiogenic potential of human adipose-derived stem cells.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre / Tejido Adiposo / Hidrogeles Límite: Humans Idioma: En Revista: Adv Healthc Mater Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre / Tejido Adiposo / Hidrogeles Límite: Humans Idioma: En Revista: Adv Healthc Mater Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania