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Evolutionary trajectories of snake genes and genomes revealed by comparative analyses of five-pacer viper.
Yin, Wei; Wang, Zong-Ji; Li, Qi-Ye; Lian, Jin-Ming; Zhou, Yang; Lu, Bing-Zheng; Jin, Li-Jun; Qiu, Peng-Xin; Zhang, Pei; Zhu, Wen-Bo; Wen, Bo; Huang, Yi-Jun; Lin, Zhi-Long; Qiu, Bi-Tao; Su, Xing-Wen; Yang, Huan-Ming; Zhang, Guo-Jie; Yan, Guang-Mei; Zhou, Qi.
Afiliación
  • Yin W; Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510089, China.
  • Wang ZJ; Life Sciences Institute, The Key Laboratory of Conservation Biology for Endangered Wildlife of the Ministry of Education, Zhejiang University, Hangzhou 310058, China.
  • Li QY; China National Genebank, BGI-Shenzhen, Shenzhen 518083, China.
  • Lian JM; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
  • Zhou Y; School of Bioscience &Bioengineering, South China University of Technology, Guangzhou 510006, China.
  • Lu BZ; China National Genebank, BGI-Shenzhen, Shenzhen 518083, China.
  • Jin LJ; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
  • Qiu PX; Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen K 1350, Denmark.
  • Zhang P; China National Genebank, BGI-Shenzhen, Shenzhen 518083, China.
  • Zhu WB; China National Genebank, BGI-Shenzhen, Shenzhen 518083, China.
  • Wen B; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510089, China.
  • Huang YJ; China National Genebank, BGI-Shenzhen, Shenzhen 518083, China.
  • Lin ZL; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510089, China.
  • Qiu BT; China National Genebank, BGI-Shenzhen, Shenzhen 518083, China.
  • Su XW; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510089, China.
  • Yang HM; BGI-Shenzhen, Shenzhen 518083, China.
  • Zhang GJ; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510089, China.
  • Yan GM; BGI-Shenzhen, Shenzhen 518083, China.
  • Zhou Q; China National Genebank, BGI-Shenzhen, Shenzhen 518083, China.
Nat Commun ; 7: 13107, 2016 10 06.
Article en En | MEDLINE | ID: mdl-27708285
Snakes have numerous features distinctive from other tetrapods and a rich history of genome evolution that is still obscure. Here, we report the high-quality genome of the five-pacer viper, Deinagkistrodon acutus, and comparative analyses with other representative snake and lizard genomes. We map the evolutionary trajectories of transposable elements (TEs), developmental genes and sex chromosomes onto the snake phylogeny. TEs exhibit dynamic lineage-specific expansion, and many viper TEs show brain-specific gene expression along with their nearby genes. We detect signatures of adaptive evolution in olfactory, venom and thermal-sensing genes and also functional degeneration of genes associated with vision and hearing. Lineage-specific relaxation of functional constraints on respective Hox and Tbx limb-patterning genes supports fossil evidence for a successive loss of forelimbs then hindlimbs during snake evolution. Finally, we infer that the ZW sex chromosome pair had undergone at least three recombination suppression events in the ancestor of advanced snakes. These results altogether forge a framework for our deep understanding into snakes' history of molecular evolution.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Serpientes / Elementos Transponibles de ADN / Evolución Biológica Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Serpientes / Elementos Transponibles de ADN / Evolución Biológica Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido