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Surgical Treatment, Oral Rehabilitation, and Orthognathic Surgery After Failure of Pharmacologic Treatment of Central Giant Cell Lesion: A Case Report.
Maia Nogueira, Renato Luiz; Osterne, Rafael Lima Verde; Cavalcante, Roberta Barroso; Abreu, Ricardo Teixeira.
Afiliación
  • Maia Nogueira RL; Associate Professor, Department of Dental Clinic, Discipline of Oral and Maxillofacial Surgery and Stomatology, Federal University of Ceara School of Dentistry, Fortaleza, Brazil; Oral and Maxillofacial Surgeon, Department of Oral and Maxillofacial Surgery, Memorial Batista Hospital, Fortaleza, Braz
  • Osterne RL; Assistant Professor, Department of Pathology, Fortaleza University School of Medicine, Fortaleza, Brazil; PhD Student, Federal University of Ceara School of Dentistry, Fortaleza, Brazil. Electronic address: rlimaverde@unifor.br.
  • Cavalcante RB; Associate Professor, Department of Oral Pathology, Fortaleza University School of Dentistry, Fortaleza, Brazil.
  • Abreu RT; Associate Professor, São Leopoldo Mandic, Fortaleza, Brazil.
J Oral Maxillofac Surg ; 74(12): 2567.e1-2567.e10, 2016 Dec.
Article en En | MEDLINE | ID: mdl-27677684
Although pharmacologic treatments for central giant cell lesions have gained much emphasis, these treatment modalities do not always have successful outcomes, and surgical treatment may be necessary. The purpose of the present study was to report a case of aggressive central giant cell lesion initially treated by nonsurgical methods without satisfactory results, necessitating segmental mandibular resection for definitive treatment and oral rehabilitation. A 20-year-old woman was diagnosed with an aggressive central giant cell lesion in the mandible. The patient was first treated with intralesional corticosteroid injections. Subsequently, the lesion increased in size. Therefore, a second pharmacologic treatment was proposed with salmon calcitonin nasal spray, but no signs of a treatment response were noted. Because of the lack of response, surgical excision was performed, and a mandibular reconstruction plate was installed. At 12 months after surgical resection, the patient underwent mandibular reconstruction with bone grafts. After 6 months, 7 dental implants were installed, and fixed prostheses were made. After installation of the prostheses, the patient experienced persistent mandibular laterognathism, and a mandibular orthognathic surgery was performed to correct the laterognathia. The follow-up examination 4 years after orthognathic surgery showed no signs of recurrence and good facial symmetry.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Granuloma de Células Gigantes / Enfermedades Mandibulares / Corticoesteroides / Procedimientos Quirúrgicos Ortognáticos / Antiinflamatorios Límite: Adult / Female / Humans Idioma: En Revista: J Oral Maxillofac Surg Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Granuloma de Células Gigantes / Enfermedades Mandibulares / Corticoesteroides / Procedimientos Quirúrgicos Ortognáticos / Antiinflamatorios Límite: Adult / Female / Humans Idioma: En Revista: J Oral Maxillofac Surg Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos