Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice.

Arora, Tulika; Wegmann, Udo; Bobhate, Anup; Lee, Ying Shiuan; Greiner, Thomas U; Drucker, Daniel J; Narbad, Arjan; Bäckhed, Fredrik

Arora, Tulika; Wegmann, Udo; Bobhate, Anup; Lee, Ying Shiuan; Greiner, Thomas U; Drucker, Daniel J; Narbad, Arjan; Bäckhed, Fredrik.

Afiliación

Arora T; Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Wegmann U; Gut Health and Food Safety Programme, Institute of Food Research, Norwich NR4 7UA, UK.
Bobhate A; Gut Health and Food Safety Programme, Institute of Food Research, Norwich NR4 7UA, UK.
Lee YS; Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Greiner TU; Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Drucker DJ; Department of Medicine, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON M5G 1X5, Canada.
Narbad A; Gut Health and Food Safety Programme, Institute of Food Research, Norwich NR4 7UA, UK.
Bäckhed F; Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden; Novo Nordisk Foundation Center for Basic Metabolic Research, Section for Metabolic Receptology a

Mol Metab ; 5(8): 725-730, 2016 Aug.

Article en En | MEDLINE | ID: mdl-27656410

Palabras clave

DPP4, Dipeptidyl peptidase 4; G-KRB, glucose-Krebs ringer buffer; G6pc, glucose 6 phosphatase, catalytic subunit; GLP-1; GLP-1, Glucagon-like peptide 1; GLP1R-KO, GLP-1 receptor knock out; Glucose tolerance; HFD, high fat diet; IPGTT, Intraperitoneal glucose tolerance test; ITT, Insulin tolerance test; LL-GLP1, GLP-1 producing recombinant strain; LL-UK200, Control vector only strain; Lactococcus lactis; Pepck, phosphoenolpyruvate carboxykinase; Recombinant bacteria; WT, Wild type; cfu, Colony forming unit

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Mol Metab Año: 2016 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Alemania

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