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Phase 1 study evaluating the safety and pharmacokinetics of pralatrexate in relapsed/refractory advanced solid tumors and lymphoma patients with mild, moderate, and severe renal impairment.
Kelly, Kevin R; Gabrail, Nashat; Weitman, Steven; Sarantopoulos, John; Olszanski, Anthony J; Edenfield, William; Venitz, Jurgen; Reddy, Guru; Yang, Allen; Hasal, Steven J; Lockhart, A Craig.
Afiliación
  • Kelly KR; Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, University of Southern California, 1441 Eastlake Ave, NOR 3465, MC 9172, Los Angeles, CA, 90033, USA. kevin.kelly@med.usc.edu.
  • Gabrail N; Gabrail Cancer Center Research, 4875 Higbee Ave. NW, Canton, OH, 44718, USA.
  • Weitman S; UT Health Science Center, Cancer Therapy and Research Center, 7979 Wurzbach Road, San Antonio, TX, 78229, USA.
  • Sarantopoulos J; UT Health Science Center, Cancer Therapy and Research Center, 7979 Wurzbach Road, San Antonio, TX, 78229, USA.
  • Olszanski AJ; Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA, 19111, USA.
  • Edenfield W; Greenville Hospital Systems Institute for Translational Oncology Research, 900 West Faris Rd CTC, 3rd Floor, CRU, Greenville, SC, 29605, USA.
  • Venitz J; Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, 410 N 12th Street, P.O. Box 980533, Richmond, VA, 23298-0533, USA.
  • Reddy G; Spectrum Pharmaceuticals, Inc., 157 Technology Dr., Irvine, CA, 92618, USA.
  • Yang A; Spectrum Pharmaceuticals, Inc., 157 Technology Dr., Irvine, CA, 92618, USA.
  • Hasal SJ; Spectrum Pharmaceuticals, Inc., 157 Technology Dr., Irvine, CA, 92618, USA.
  • Lockhart AC; Washington University School of Medicine, 660 Euclid Avenue, St. Louis, MO, 63110, USA.
Cancer Chemother Pharmacol ; 78(5): 929-939, 2016 Nov.
Article en En | MEDLINE | ID: mdl-27638045
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Renal / Antagonistas del Ácido Fólico / Aminopterina / Linfoma / Neoplasias Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Chemother Pharmacol Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Renal / Antagonistas del Ácido Fólico / Aminopterina / Linfoma / Neoplasias Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Chemother Pharmacol Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania