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Role of Metabolomics in Traumatic Brain Injury Research.
Wolahan, Stephanie M; Hirt, Daniel; Braas, Daniel; Glenn, Thomas C.
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  • Wolahan SM; UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095, USA; Department of Neurosurgery, David Geffen School of Medicine at UCLA, 300 Stein Plaza, Los Angeles, CA 90095-6901, USA.
  • Hirt D; UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095, USA; Department of Neurosurgery, David Geffen School of Medicine at UCLA, 300 Stein Plaza, Los Angeles, CA 90095-6901, USA.
  • Braas D; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, 570 Westwood Plaza, Los Angeles, CA 90095-1735, USA; UCLA Metabolomics and Proteomics Center, 570 Westwood Plaza, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Glenn TC; UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095, USA; Department of Neurosurgery, David Geffen School of Medicine at UCLA, 300 Stein Plaza, Los Angeles, CA 90095-6901, USA. Electronic address: TGlenn@mednet.ucla.edu.
Neurosurg Clin N Am ; 27(4): 465-72, 2016 Oct.
Article en En | MEDLINE | ID: mdl-27637396
Metabolomics is an important member of the omics community in that it defines which small molecules may be responsible for disease states. This article reviews the essential principles of metabolomics from specimen preparation, chemical analysis, to advanced statistical methods. Metabolomics in traumatic brain injury has so far been underutilized. Future metabolomics-based studies focused on the diagnoses, prognoses, and treatment effects need to be conducted across all types of traumatic brain injury.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Investigación / Metabolómica / Lesiones Traumáticas del Encéfalo Límite: Humans Idioma: En Revista: Neurosurg Clin N Am Asunto de la revista: NEUROCIRURGIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Investigación / Metabolómica / Lesiones Traumáticas del Encéfalo Límite: Humans Idioma: En Revista: Neurosurg Clin N Am Asunto de la revista: NEUROCIRURGIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos