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Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization.
Hernández-Tiedra, Sonia; Fabriàs, Gemma; Dávila, David; Salanueva, Íñigo J; Casas, Josefina; Montes, L Ruth; Antón, Zuriñe; García-Taboada, Elena; Salazar-Roa, María; Lorente, Mar; Nylandsted, Jesper; Armstrong, Jane; López-Valero, Israel; McKee, Christopher S; Serrano-Puebla, Ana; García-López, Roberto; González-Martínez, José; Abad, José L; Hanada, Kentaro; Boya, Patricia; Goñi, Félix; Guzmán, Manuel; Lovat, Penny; Jäättelä, Marja; Alonso, Alicia; Velasco, Guillermo.
Afiliación
  • Hernández-Tiedra S; a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.
  • Fabriàs G; b Instituto de Investigaciones Sanitarias San Carlos (IdISSC) , Madrid , Spain.
  • Dávila D; c Research Unit on BioActive Molecules (RUBAM) , Departments of Biomedicinal Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) , Barcelona , Spain.
  • Salanueva ÍJ; a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.
  • Casas J; b Instituto de Investigaciones Sanitarias San Carlos (IdISSC) , Madrid , Spain.
  • Montes LR; a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.
  • Antón Z; c Research Unit on BioActive Molecules (RUBAM) , Departments of Biomedicinal Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) , Barcelona , Spain.
  • García-Taboada E; d Biofisika Institute (UPV/EHU, CSIC) , and Departamento de Bioquímica, Universidad del País Vasco, Barrio Sarriena s/n , Leioa , Spain.
  • Salazar-Roa M; d Biofisika Institute (UPV/EHU, CSIC) , and Departamento de Bioquímica, Universidad del País Vasco, Barrio Sarriena s/n , Leioa , Spain.
  • Lorente M; a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.
  • Nylandsted J; a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.
  • Armstrong J; a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.
  • López-Valero I; b Instituto de Investigaciones Sanitarias San Carlos (IdISSC) , Madrid , Spain.
  • McKee CS; e Unit of Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center (DCRC) , Copenhagen , Denmark.
  • Serrano-Puebla A; f Dermatological Sciences , Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne , UK.
  • García-López R; g Faculty of Applied Sciences, University of Sunderland , Sunderland , UK.
  • González-Martínez J; a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.
  • Abad JL; b Instituto de Investigaciones Sanitarias San Carlos (IdISSC) , Madrid , Spain.
  • Hanada K; f Dermatological Sciences , Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne , UK.
  • Boya P; a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.
  • Goñi F; h Departament of Cellular and Molecular Biology , Centro de Investigaciones Biológicas, CSIC , Madrid , Spain.
  • Guzmán M; a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.
  • Lovat P; a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.
  • Jäättelä M; b Instituto de Investigaciones Sanitarias San Carlos (IdISSC) , Madrid , Spain.
  • Alonso A; c Research Unit on BioActive Molecules (RUBAM) , Departments of Biomedicinal Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) , Barcelona , Spain.
  • Velasco G; i Department of Biochemistry and Cell Biology , National Institute of Infectious Diseases , Shinjuku-ku, Tokyo , Japan.
Autophagy ; 12(11): 2213-2229, 2016 11.
Article en En | MEDLINE | ID: mdl-27635674
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Ceramidas / Apoptosis / Lisosomas / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Autophagy Año: 2016 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Ceramidas / Apoptosis / Lisosomas / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Autophagy Año: 2016 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos