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Oral intake of added titanium dioxide and its nanofraction from food products, food supplements and toothpaste by the Dutch population.
Rompelberg, Cathy; Heringa, Minne B; van Donkersgoed, Gerda; Drijvers, José; Roos, Agnes; Westenbrink, Susanne; Peters, Ruud; van Bemmel, Greet; Brand, Walter; Oomen, Agnes G.
Afiliación
  • Rompelberg C; a National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands and.
  • Heringa MB; a National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands and.
  • van Donkersgoed G; a National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands and.
  • Drijvers J; a National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands and.
  • Roos A; a National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands and.
  • Westenbrink S; a National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands and.
  • Peters R; b RIKILT - Wageningen University & Research Centre , Wageningen , The Netherlands.
  • van Bemmel G; b RIKILT - Wageningen University & Research Centre , Wageningen , The Netherlands.
  • Brand W; a National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands and.
  • Oomen AG; a National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands and.
Nanotoxicology ; 10(10): 1404-1414, 2016 12.
Article en En | MEDLINE | ID: mdl-27619007
Titanium dioxide (TiO2) is commonly applied to enhance the white colour and brightness of food products. TiO2 is also used as white pigment in other products such as toothpaste. A small fraction of the pigment is known to be present as nanoparticles (NPs). Recent studies with TiO2 NPs indicate that these particles can have toxic effects. In this paper, we aimed to estimate the oral intake of TiO2 and its NPs from food, food supplements and toothpaste in the Dutch population aged 2 to over 70 years by combining data on food consumption and supplement intake with concentrations of Ti and TiO2 NPs in food products and supplements. For children aged 2-6 years, additional intake via ingestion of toothpaste was estimated. The mean long-term intake to TiO2 ranges from 0.06 mg/kg bw/day in elderly (70+), 0.17 mg/kg bw/day for 7-69-year-old people, to 0.67 mg/kg bw/day in children (2-6 year old). The estimated mean intake of TiO2 NPs ranges from 0.19 µg/kg bw/day in elderly, 0.55 µg/kg bw/day for 7-69-year-old people, to 2.16 µg/kg bw/day in young children. Ninety-fifth percentile (P95) values are 0.74, 1.61 and 4.16 µg/kg bw/day, respectively. The products contributing most to the TiO2 intake are toothpaste (in young children only), candy, coffee creamer, fine bakery wares and sauces. In a separate publication, the results are used to evaluate whether the presence of TiO2 NPs in these products can pose a human health risk.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Titanio / Pastas de Dientes / Suplementos Dietéticos / Ingestión de Alimentos / Exposición a Riesgos Ambientales / Nanopartículas Límite: Adolescent / Adult / Aged / Child / Child, preschool / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Nanotoxicology Asunto de la revista: TOXICOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Reino Unido
Buscar en Google
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Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Titanio / Pastas de Dientes / Suplementos Dietéticos / Ingestión de Alimentos / Exposición a Riesgos Ambientales / Nanopartículas Límite: Adolescent / Adult / Aged / Child / Child, preschool / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Nanotoxicology Asunto de la revista: TOXICOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Reino Unido