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Gene Expression Patterns in Peripheral Blood Leukocytes in Patients with Recurrent Ciguatera Fish Poisoning: Preliminary Studies.
Lopez, Maria-Cecilia; Ungaro, Ricardo F; Baker, Henry V; Moldawer, Lyle L; Robertson, Alison; Abbott, Margaret; Roberts, Sparkle M; Grattan, Lynn M; Morris, J Glenn.
Afiliación
  • Lopez MC; Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL, 32610.
  • Ungaro RF; Department of Surgery, College of Medicine, University of Florida, Gainesville, FL 32610.
  • Baker HV; Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL, 32610; Department of Surgery, College of Medicine, University of Florida, Gainesville, FL 32610; Genetics Institute, University of Florida, Gainesville, FL 32610.
  • Moldawer LL; Department of Surgery, College of Medicine, University of Florida, Gainesville, FL 32610.
  • Robertson A; Marine Ecotoxicology Lab, Department of Marine Sciences, University of South Alabama & Dauphin Island Sea Lab.
  • Abbott M; Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610.
  • Roberts SM; Department of Neurology: Division of Neuropsychology, University of Maryland School of Medicine, 110 S. Paca St. 3 Floor, Baltimore, MD 21201.
  • Grattan LM; Department of Neurology: Division of Neuropsychology, University of Maryland School of Medicine, 110 S. Paca St. 3 Floor, Baltimore, MD 21201.
  • Morris JG; Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610; Department of Medicine, College of Medicine, Emerging Pathogens Institute, University of Florida, 2055 Mowry Road; Box 100009, Gainesville, FL 32610.
Harmful Algae ; 57(B): 35-38, 2016 Jul.
Article en En | MEDLINE | ID: mdl-27594814
Ciguatera fish poisoning (ciguatera) is a common clinical syndrome in areas where there is dependence on tropical reef fish for food. A subset of patients develops recurrent and, in some instances, chronic symptoms, which may result in substantial disability. To identify possible biomarkers for recurrent/chronic disease, and to explore correlations with immune gene expression, peripheral blood leukocyte gene expression in 10 ciguatera patients (7 recurrent, 3 acute) from the U.S. Virgin Islands, and 5 unexposed Florida controls were evaluated. Significant differences in gene expression were noted when comparing ciguatera patients and controls; however, it was not possible to differentiate between patients with acute and recurrent disease, possibly due to the small sample sizes involved.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Harmful Algae Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Harmful Algae Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos