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Antioxidant activity of milk protein hydrolysate in alloxan-induced diabetic rats.
Awad, S; El-Sayed, M I; Wahba, A; El Attar, A; Yousef, M I; Zedan, M.
Afiliación
  • Awad S; Department of Dairy Science and Technology, Faculty of Agriculture, Alexandria University, Alexandria 21545, Egypt. Electronic address: sameh111eg@yahoo.com.
  • El-Sayed MI; Department of Dairy Science and Technology, Faculty of Agriculture, Alexandria University, Alexandria 21545, Egypt; Department of Dairy Technology Research, Food Technology Research Institute, ARC, Giza 12622, Egypt.
  • Wahba A; Department of Dairy Science and Technology, Faculty of Agriculture, Alexandria University, Alexandria 21545, Egypt.
  • El Attar A; Department of Dairy Science and Technology, Faculty of Agriculture, Alexandria University, Alexandria 21545, Egypt.
  • Yousef MI; Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria 21526, Egypt.
  • Zedan M; Department of Dairy Technology Research, Food Technology Research Institute, ARC, Giza 12622, Egypt.
J Dairy Sci ; 99(11): 8499-8510, 2016 Nov.
Article en En | MEDLINE | ID: mdl-27592424
We investigated the effects of milk protein concentrate (MPC) and milk protein concentrate hydrolysate (MPCH) as antioxidant agents in rats. Six groups of healthy (non-diabetic) and type-II diabetic rats were used: (1) healthy rats (control), (2) alloxan-induced rats (diabetic control group), (3) healthy rats treated orally with MPC, (4) diabetic rats treated orally with MPC, (5) healthy rats treated orally with MPCH, and (6) diabetic rats treated orally with MPCH. We concluded that treatment with MPC or MPCH reduced the level of thiobarbituric acid reactive substances in healthy and diabetic rats. Treatment with MPC or MPCH improved activities of antioxidant enzymes (catalase, superoxide dismutase, reduced glutathione, glutathione-S-transferase, and glutathione peroxidase) in healthy and diabetic rats. From the present data, we concluded that both MPC and MPCH contain potent antioxidants and could improve the health of rats or other animals with diabetes mellitus.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hidrolisados de Proteína / Aloxano Límite: Animals Idioma: En Revista: J Dairy Sci Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hidrolisados de Proteína / Aloxano Límite: Animals Idioma: En Revista: J Dairy Sci Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos