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A systematic review and meta-analysis of outcomes of transcatheter stent implantation for the primary treatment of native coarctation.
Yang, Linqi; Chua, Xiuzhen; Rajgor, Dimple D; Tai, Bee Choo; Quek, Swee Chye.
Afiliación
  • Yang L; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore. Electronic address: linqi_yang@nuhs.edu.sg.
  • Chua X; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore. Electronic address: xiuzhen_chua@nuhs.edu.sg.
  • Rajgor DD; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore. Electronic address: paerdd@nus.edu.sg.
  • Tai BC; Saw Swee Hock School of Public Health, National University of Singapore, Singapore. Electronic address: bee_choo_tai@nuhs.edu.sg.
  • Quek SC; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore. Electronic address: swee_chye_quek@nuhs.edu.sg.
Int J Cardiol ; 223: 1025-1034, 2016 Nov 15.
Article en En | MEDLINE | ID: mdl-27592045
BACKGROUND/OBJECTIVES: The treatment of native coarctation of aorta (CoA) has evolved since surgery performed in 1944, followed by transcatheter balloon angioplasty and recently, widely adopted stent implantation. Despite good results demonstrated with stent implantation, a systematic review and meta-analysis (SRMA) looking at the efficacy and safety of the intervention, particularly in younger population is yet to be done. We aimed to obtain pooled estimates of the success and complication rates after transcatheter stent implantation in the treatment of native CoA based on SRMA. METHODS: We searched literature published until 31 Dec. 2015, reporting outcomes of transcatheter stent implantation in the treatment of native CoA. The pooled estimates were obtained using the random effect model. RESULTS: Seventeen reports comprising 561 patients were included. Fourteen studies reported 100% success rate, the lowest was 77%, the largest study reported 81% using a definition of systolic pressure difference of less than 15mmHg. The pooled estimate of overall success rate was 98% (95% CI: 94.5-100.0; I2=65%, heterogeneity test p<0.001). Six out of 17 studies reported zero complication. Two studies, however, reported complications in almost half of the cohort. The pooled estimate of rate of complications was 10% (95% CI: 5.1-15.5; I2=72%, heterogeneity test p<0.001). Three studies comprising only children, 62, with mean age of 11.1 (4-19) years reported high mean success rate at 98% with only 1 failure. CONCLUSIONS: There is a high success rate with a small complication rate with stent implantations for native CoA even as the treatment is brought to younger age group.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Coartación Aórtica / Cateterismo Cardíaco / Implantación de Prótesis de Válvulas Cardíacas Tipo de estudio: Systematic_reviews Límite: Child / Humans Idioma: En Revista: Int J Cardiol Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Coartación Aórtica / Cateterismo Cardíaco / Implantación de Prótesis de Válvulas Cardíacas Tipo de estudio: Systematic_reviews Límite: Child / Humans Idioma: En Revista: Int J Cardiol Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos