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In Vitro Biocompatibility of Si Alloyed Multi-Principal Element Carbide Coatings.
Vladescu, Alina; Titorencu, Irina; Dekhtyar, Yuri; Jinga, Victor; Pruna, Vasile; Balaceanu, Mihai; Dinu, Mihaela; Pana, Iulian; Vendina, Viktorija; Braic, Mariana.
Afiliación
  • Vladescu A; National Institute for Optoelectronics, Magurele-Bucharest, Romania.
  • Titorencu I; Institute of Cellular Biology and Pathology "Nicolae Simionescu" of the Romanian Academy, Bucharest, Romania.
  • Dekhtyar Y; Riga Technical University, 1Kalkustr, Riga, Latvia.
  • Jinga V; Institute of Cellular Biology and Pathology "Nicolae Simionescu" of the Romanian Academy, Bucharest, Romania.
  • Pruna V; Institute of Cellular Biology and Pathology "Nicolae Simionescu" of the Romanian Academy, Bucharest, Romania.
  • Balaceanu M; National Institute for Optoelectronics, Magurele-Bucharest, Romania.
  • Dinu M; National Institute for Optoelectronics, Magurele-Bucharest, Romania.
  • Pana I; National Institute for Optoelectronics, Magurele-Bucharest, Romania.
  • Vendina V; Faculty of Physics, Bucharest University, Magurele-Bucharest, Romania.
  • Braic M; Riga Technical University, 1Kalkustr, Riga, Latvia.
PLoS One ; 11(8): e0161151, 2016.
Article en En | MEDLINE | ID: mdl-27571361
In the current study, we have examined the possibility to improve the biocompatibility of the (TiZrNbTaHf)C through replacement of either Ti or Ta by Si. The coatings were deposited on Si and 316L stainless steel substrates by magnetron sputtering in an Ar+CH4 mixed atmosphere and were examined for elemental composition, chemical bonds, surface topography, surface electrical charge and biocompatible characteristics. The net surface charge was evaluated at nano and macroscopic scale by measuring the electrical potential and work function, respectively. The biocompatible tests comprised determination of cell viability and cell attachment to the coated surface. The deposited coatings had C/(metal+Si) ratios close to unity, while a mixture of metallic carbide, free-carbon and oxidized species formed on the film surface. The coatings' surfaces were smooth and no influence of surface roughness on electrical charge or biocompatibility was found. The biocompatible characteristics correlated well with the electrical potential/work function, suggesting a significant role of surface charge in improving biocompatibility, particularly cell attachment to coating's surface. Replacement of either Ti or Ta by Si in the (TiZrNbTaHf)C coating led to an enhanced surface electrical charge, as well as to superior biocompatible properties, with best results for the (TiZrNbSiHf)C coating.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Silicio / Tantalio / Titanio / Materiales Biocompatibles Revestidos / Aleaciones Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Silicio / Tantalio / Titanio / Materiales Biocompatibles Revestidos / Aleaciones Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Estados Unidos