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Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB.
Romm, Horst; Ainsbury, Elizabeth A; Barquinero, Joan Francesc; Barrios, Leonardo; Beinke, Christina; Cucu, Alexandra; Domene, Mercedes Moreno; Filippi, Silvia; Monteiro Gil, Octávia; Gregoire, Eric; Hadjidekova, Valeria; Hatzi, Vasia; Lindholm, Carita; M Kacher, Radhia; Montoro, Alegria; Moquet, Jayne; Noditi, Mihaela; Oestreicher, Ursula; Palitti, Fabrizio; Pantelias, Gabriel; Prieto, María Jesús; Popescu, Irina; Rothkamm, Kai; Sebastià, Natividad; Sommer, Sylwester; Terzoudi, Georgia; Testa, Antonella; Wojcik, Andrzej.
Afiliación
  • Romm H; a Bundesamt fuer Strahlenschutz , Neuherberg , Germany.
  • Ainsbury EA; b Public Health England, CRCE , Chilton , Didcot , UK.
  • Barquinero JF; c Universitat Autònoma de Barcelona , Barcelona , Spain.
  • Barrios L; c Universitat Autònoma de Barcelona , Barcelona , Spain.
  • Beinke C; d Bundeswehr Institute of Radiobiology affiliated to the University of Ulm , Munich , Germany.
  • Cucu A; e Institutul National de Sanatate Publica , Bucharest , Romania.
  • Domene MM; f Servicio Madrileño de Salud - Hospital General Universitario Gregorio Marañón , Madrid , Spain.
  • Filippi S; g Department of Ecological and Biological Sciences , University of Tuscia , Viterbo , Italy.
  • Monteiro Gil O; h Centro de Ciêincias e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa , Lisboa , Portugal.
  • Gregoire E; i Institut de Radioprotection et de Sûreté Nucléaire , Fontenay-aux-Roses , France.
  • Hadjidekova V; j National Centre for Radiobiology and Radiation Protection , Sofia , Bulgaria.
  • Hatzi V; k National Centre for Scientific Research 'Demokritos' , Athens , Greece.
  • Lindholm C; l Radiation and Nuclear Safety Authority , Helsinki , Finland.
  • M Kacher R; m Commissariat à l´â€ŠÉnergie Atomique , Paris , France.
  • Montoro A; n Cell Environment , Paris , France.
  • Moquet J; o Hospital Universitario y Politécnico la Fe , Valencia , Spain.
  • Noditi M; b Public Health England, CRCE , Chilton , Didcot , UK.
  • Oestreicher U; e Institutul National de Sanatate Publica , Bucharest , Romania.
  • Palitti F; a Bundesamt fuer Strahlenschutz , Neuherberg , Germany.
  • Pantelias G; g Department of Ecological and Biological Sciences , University of Tuscia , Viterbo , Italy.
  • Prieto MJ; k National Centre for Scientific Research 'Demokritos' , Athens , Greece.
  • Popescu I; f Servicio Madrileño de Salud - Hospital General Universitario Gregorio Marañón , Madrid , Spain.
  • Rothkamm K; e Institutul National de Sanatate Publica , Bucharest , Romania.
  • Sebastià N; p University Medical Centre Hamburg-Eppendorf , Hamburg , Germany.
  • Sommer S; o Hospital Universitario y Politécnico la Fe , Valencia , Spain.
  • Terzoudi G; q Institut Chemii i Techniki Jadrowej , Warszawa , Poland.
  • Testa A; k National Centre for Scientific Research 'Demokritos' , Athens , Greece.
  • Wojcik A; r Agenzia Nazionale per le Nuove Tecnologie, l'Energia e lo Sviluppo Economico Sostenibile , Rome , Italy.
Int J Radiat Biol ; 93(1): 110-117, 2017 01.
Article en En | MEDLINE | ID: mdl-27547893
PURPOSE: To establish a training data set of digital images and to investigate the scoring criteria and dose assessment of the dicentric assay within the European network of biodosimetry (RENEB), a web based scoring inter-comparison was undertaken by 17 RENEB partners. MATERIALS AND METHODS: Two sets of 50 high resolution images were uploaded onto the RENEB website. One set included metaphases after a moderate exposure (1.3 Gy) and the other set consisted of metaphases after a high dose exposure (3.5 Gy). The laboratories used their own calibration curves for estimating doses based on observed aberration frequencies. RESULTS: The dose estimations and 95% confidence limits were compared to the actual doses and the corresponding z-values were satisfactory for the majority; only the dose estimations from two laboratories were too low or too high. The coefficients of variation were 17.6% for the moderate and 11.2% for the high dose. Metaphases with controversial results could be identified for training purposes. CONCLUSIONS: Overall, the web based scoring of the two galleries by the 17 laboratories produced very good results. Application of web based scoring for the dicentric assay may therefore be a relevant strategy for an operational biodosimetry assistance network.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bioensayo / Linfocitos / Monitoreo de Radiación / Exposición a la Radiación / Internet / Análisis Citogenético Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Int J Radiat Biol Asunto de la revista: RADIOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bioensayo / Linfocitos / Monitoreo de Radiación / Exposición a la Radiación / Internet / Análisis Citogenético Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Int J Radiat Biol Asunto de la revista: RADIOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido