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Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors.
Zak, Mark; Yuen, Po-Wai; Liu, Xiongcai; Patel, Snahel; Sampath, Deepak; Oeh, Jason; Liederer, Bianca M; Wang, Weiru; O'Brien, Thomas; Xiao, Yang; Skelton, Nicholas; Hua, Rongbao; Sodhi, Jasleen; Wang, Yunli; Zhang, Lei; Zhao, Guiling; Zheng, Xiaozhang; Ho, Yen-Ching; Bair, Kenneth W; Dragovich, Peter S.
Afiliación
  • Zak M; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Yuen PW; Pharmaron Beijing Co. Ltd. , 6 Taihe Road, BDA, Beijing 100176, PR China.
  • Liu X; Pharmaron Beijing Co. Ltd. , 6 Taihe Road, BDA, Beijing 100176, PR China.
  • Patel S; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Sampath D; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Oeh J; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Liederer BM; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Wang W; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • O'Brien T; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Xiao Y; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Skelton N; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Hua R; Pharmaron Beijing Co. Ltd. , 6 Taihe Road, BDA, Beijing 100176, PR China.
  • Sodhi J; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Wang Y; Pharmaron Beijing Co. Ltd. , 6 Taihe Road, BDA, Beijing 100176, PR China.
  • Zhang L; Pharmaron Beijing Co. Ltd. , 6 Taihe Road, BDA, Beijing 100176, PR China.
  • Zhao G; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Zheng X; FORMA Therapeutics Inc. , 500 Arsenal Street, Watertown, Massachusetts 02472, United States.
  • Ho YC; FORMA Therapeutics Inc. , 500 Arsenal Street, Watertown, Massachusetts 02472, United States.
  • Bair KW; FORMA Therapeutics Inc. , 500 Arsenal Street, Watertown, Massachusetts 02472, United States.
  • Dragovich PS; Genentech Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
J Med Chem ; 59(18): 8345-68, 2016 09 22.
Article en En | MEDLINE | ID: mdl-27541271
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridinas / Inhibidores Enzimáticos / Nicotinamida Fosforribosiltransferasa / Citocromo P-450 CYP2C9 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridinas / Inhibidores Enzimáticos / Nicotinamida Fosforribosiltransferasa / Citocromo P-450 CYP2C9 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos