Morphologic and molecular changes in the placenta: what we can learn from environmental exposures.
Fertil Steril
; 106(4): 930-40, 2016 09 15.
Article
en En
| MEDLINE
| ID: mdl-27523298
In mammals, the extraembryonic tissues, which include the placenta, are crucial for embryonic development and growth. Because the placenta is no longer needed for postnatal life, however, it has been relatively understudied as a tissue of interest in biomedical research. Recently, increased efforts have been placed on understanding the placenta and how it may play a key role in human health and disease. In this review, we discuss two very different types of environmental exposures: assisted reproductive technologies and in utero exposure to endocrine-disrupting chemicals. We summarize the current literature on their effects on placental development in both rodent and human, and comment on the potential use of placental biomarkers as predictors of offspring health outcomes.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Placenta
/
Reproducción
/
Exposición Materna
/
Técnicas Reproductivas Asistidas
/
Contaminantes Ambientales
/
Disruptores Endocrinos
/
Fármacos para la Fertilidad Femenina
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Animals
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Fertil Steril
Año:
2016
Tipo del documento:
Article
Pais de publicación:
Estados Unidos