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High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML.
Zhao, Yue; Liu, Qi; Acharya, Pankaj; Stengel, Kristy R; Sheng, Quanhu; Zhou, Xiaofan; Kwak, Hojoong; Fischer, Melissa A; Bradner, James E; Strickland, Stephen A; Mohan, Sanjay R; Savona, Michael R; Venters, Bryan J; Zhou, Ming-Ming; Lis, John T; Hiebert, Scott W.
Afiliación
  • Zhao Y; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Liu Q; Center for Quantitative Sciences, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Acharya P; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Stengel KR; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Sheng Q; Center for Quantitative Sciences, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Zhou X; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37212, USA.
  • Kwak H; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
  • Fischer MA; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Bradner JE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  • Strickland SA; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Mohan SR; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Savona MR; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Venters BJ; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Zhou MM; Department of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Lis JT; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
  • Hiebert SW; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. Electronic address: scott.hiebert@vanderbilt.edu.
Cell Rep ; 16(7): 2003-16, 2016 08 16.
Article en En | MEDLINE | ID: mdl-27498870
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Translocación Genética / ARN Polimerasas Dirigidas por ADN / Proteínas / Regulación Leucémica de la Expresión Génica / Proteínas Proto-Oncogénicas c-kit / Resistencia a Antineoplásicos / Proteína 1 de la Secuencia de Leucemia de Células Mieloides Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Cell Rep Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Translocación Genética / ARN Polimerasas Dirigidas por ADN / Proteínas / Regulación Leucémica de la Expresión Génica / Proteínas Proto-Oncogénicas c-kit / Resistencia a Antineoplásicos / Proteína 1 de la Secuencia de Leucemia de Células Mieloides Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Cell Rep Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos