Kinetic and thermodynamic framework for P4-P6 RNA reveals tertiary motif modularity and modulation of the folding preferred pathway.

Bisaria, Namita; Greenfeld, Max; Limouse, Charles; Pavlichin, Dmitri S; Mabuchi, Hideo; Herschlag, Daniel

Bisaria, Namita; Greenfeld, Max; Limouse, Charles; Pavlichin, Dmitri S; Mabuchi, Hideo; Herschlag, Daniel.

Afiliación

Bisaria N; Department of Biochemistry, Stanford University, Stanford, CA 94305;
Greenfeld M; Department of Biochemistry, Stanford University, Stanford, CA 94305; Department of Chemical Engineering, Stanford University, Stanford, CA 94305;
Limouse C; Department of Applied Physics, Stanford University, Stanford, CA 94305;
Pavlichin DS; Department of Applied Physics, Stanford University, Stanford, CA 94305;
Mabuchi H; Department of Applied Physics, Stanford University, Stanford, CA 94305;
Herschlag D; Department of Biochemistry, Stanford University, Stanford, CA 94305; Department of Chemical Engineering, Stanford University, Stanford, CA 94305; Department of Chemistry, Stanford University, Stanford, CA 94305 herschla@stanford.edu.

Proc Natl Acad Sci U S A ; 113(34): E4956-65, 2016 08 23.

Article en En | MEDLINE | ID: mdl-27493222

Asunto(s)

Motivos de Nucleótidos; Mutación Puntual; ARN/química; Emparejamiento Base; Transferencia Resonante de Energía de Fluorescencia; Cinética; Modelos Moleculares; ARN/genética; Pliegue del ARN; Imagen Individual de Molécula/métodos; Termodinámica

Palabras clave

RNA folding; RNA tertiary motifs; folding pathways; kinetics; single-molecule FRET

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN / Mutación Puntual / Motivos de Nucleótidos Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos

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