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Copulatory plugs inhibit the reproductive success of rival males.
Mangels, Rachel; Tsung, Kathleen; Kwan, Kelly; Dean, Matthew D.
Afiliación
  • Mangels R; Molecular and Computational Biology, University of Southern California, 1050 Childs Way, Los Angeles, CA 90089.
  • Tsung K; Molecular and Computational Biology, University of Southern California, 1050 Childs Way, Los Angeles, CA 90089.
  • Kwan K; Molecular and Computational Biology, University of Southern California, 1050 Childs Way, Los Angeles, CA 90089.
  • Dean MD; Molecular and Computational Biology, University of Southern California, 1050 Childs Way, Los Angeles, CA 90089.
J Evol Biol ; 29(11): 2289-2296, 2016 11.
Article en En | MEDLINE | ID: mdl-27488082
Ejaculated proteins play important roles in reproductive fitness. In many species, seminal fluid coagulates and forms what has been referred to as a copulatory plug in the female's reproductive tract. In mice, previous work demonstrated that knockout males missing a key seminal fluid protein were unable to form a plug and less successful at siring litters in noncompetitive matings (one female, one male), probably the result of reduced sperm transport or insufficient stimulation of the female. Here, we extend these previous studies to competitive matings (one female, two males) and make two key insights. First, when first males were unable to form a plug, they lost almost all paternity to second males to mate. Thus, the copulatory plugs of second males could not rescue the reduced fertility of first males. Second, we showed that the copulatory plug of first males effectively blocked fertilization by second males, even if first males were vasectomized. Taken together, our experiments demonstrated that first males lost almost all paternity if they never formed a plug. We discuss our results in the context of natural populations, where in spite of the strong effects seen here, pregnant female mice regularly carry litters fertilized by more than one male.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Espermatozoides / Copulación Límite: Animals / Pregnancy Idioma: En Revista: J Evol Biol Asunto de la revista: BIOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Espermatozoides / Copulación Límite: Animals / Pregnancy Idioma: En Revista: J Evol Biol Asunto de la revista: BIOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Suiza