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Optical coherence tomography characteristics of different types of big bubbles seen in deep anterior lamellar keratoplasty by the big bubble technique.
AlTaan, S L; Termote, K; Elalfy, M S; Hogan, E; Werkmeister, R; Schmetterer, L; Holland, S; Dua, H S.
Afiliación
  • AlTaan SL; Larry A Donoso Laboratory for Eye Research, Section of Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK.
  • Termote K; University of British Columbia Vancouver, Vancouver, BC, Canada.
  • Elalfy MS; Department of Ophthalmology, University Hospital Brussels, Brussels, Belgium.
  • Hogan E; Larry A Donoso Laboratory for Eye Research, Section of Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK.
  • Werkmeister R; Larry A Donoso Laboratory for Eye Research, Section of Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK.
  • Schmetterer L; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
  • Holland S; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
  • Dua HS; Department of Clinical Pharmacology, Medical University of Vienna, Austria.
Eye (Lond) ; 30(11): 1509-1516, 2016 Nov.
Article en En | MEDLINE | ID: mdl-27472215
PurposeTo define optical coherence tomography (OCT) characteristics of type-1, type-2, and mixed big bubbles (BB) seen in deep anterior lamellar keratoplasty.MethodsHuman sclero-corneal discs were obtained from UK (30) and Canada (16) eye banks. Air was injected into corneal stroma until a BB formed. UK samples were fixed in formalin before scanning with Fourier-domain (FD-OCT). One pair of each type of BB was scanned fresh. All BB obtained from Canada were scanned fresh with time-domain (TD-OCT). For each OCT machine used, type-1 BB from which Descemets membrane (DM) was partially peeled, were also scanned. The morphological characteristics of the scans were studied.ResultsFD-OCT of the posterior wall of type-1 (Dua's layer (DL) with DM) and type-2 BB (DM alone) both revealed a double-contour hyper-reflective curvilinear image with a hypo-reflective zone in between. The anterior line of type-2 BB was thinner than that seen with type-1 BB. In mixed BB, FD-OCT showed two separate curvilinear images. The anterior image was a single hyper-reflective line (DL), whereas the posterior image, representing the posterior wall of type-2 BB (DM) was made of two hyper-reflective lines with a dark space in between. TD-OCT images were similar with less defined component lines, but the entire extent of the BB could be visualised.ConclusionOn OCT examination the DM and DL present distinct features, which can help identify type-1, type-2, and mixed BB. These characteristics will help corneal surgeons interpret intraoperative OCT during lamellar corneal surgery.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vacuolas / Trasplante de Córnea / Córnea / Sustancia Propia / Tomografía de Coherencia Óptica / Lámina Limitante Posterior Tipo de estudio: Prognostic_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eye (Lond) Asunto de la revista: OFTALMOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vacuolas / Trasplante de Córnea / Córnea / Sustancia Propia / Tomografía de Coherencia Óptica / Lámina Limitante Posterior Tipo de estudio: Prognostic_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eye (Lond) Asunto de la revista: OFTALMOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Reino Unido