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Anthelmintic activity of silver-extract nanoparticles synthesized from the combination of silver nanoparticles and M. charantia fruit extract.
Rashid, Md Mamun Or; Ferdous, Jannatul; Banik, Sujan; Islam, Md Rabiul; Uddin, A H M Mazbah; Robel, Fataha Nur.
Afiliación
  • Rashid MM; Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali, 3814, Bangladesh. mamun_nstu@yahoo.com.
  • Ferdous J; Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali, 3814, Bangladesh.
  • Banik S; Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali, 3814, Bangladesh.
  • Islam MR; Department of Pharmacy, International Islamic University Chittagong, Chandgaon R/A, Chittagong, Bangladesh.
  • Uddin AH; Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali, 3814, Bangladesh.
  • Robel FN; Department of Applied Chemistry and Chemical Engineering, Noakhali Science and Technology University, Sonapur, Noakhali, 3814, Bangladesh.
BMC Complement Altern Med ; 16: 242, 2016 Jul 26.
Article en En | MEDLINE | ID: mdl-27457362
BACKGROUND: Present study has been conducted to know the anthelmintic activity of polyaniline coated silver nanoparticles (AgNPs) synthesized from Momordica charantia fruit extract. METHODS: By reduction of AgNO3 in presence of NaBH4, silver nanoparticles were prepared. After mixing silver nanoparticles and extracts, coating was given on nanoparticles using polyaniline. Prepared nanoparticles were characterized by Visual, UV, FTIR spectroscopy, SEM techniques, and TEM analysis. RESULTS: The FTIR results implied that AgNPs were successfully synthesized and capped with bio-compounds present in the extract. The result showed that death times of worm were 35.12 ± 0.5 and 59.3 ± 0.3 minutes for M. charantia extract and Ag-nanoparticles individually. But when these two combined together, paralysis and death time fall drastically which were only 6.16 ± 0.6 and 9.1 ± 0.4 minutes respectively. Albendazole tablet was used as standard, which made worms death in 3.66 ± 0.1 minutes. CONCLUSION: Ag-Extract NPs showed strong anthelmintic activity against worm. This study has paved the way for further research to design new anthelmintic drug from the combination of M. charantia and AgNPs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plata / Extractos Vegetales / Momordica charantia / Nanopartículas del Metal / Antihelmínticos Límite: Animals Idioma: En Revista: BMC Complement Altern Med Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2016 Tipo del documento: Article País de afiliación: Bangladesh Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plata / Extractos Vegetales / Momordica charantia / Nanopartículas del Metal / Antihelmínticos Límite: Animals Idioma: En Revista: BMC Complement Altern Med Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2016 Tipo del documento: Article País de afiliación: Bangladesh Pais de publicación: Reino Unido