Gentisic acid sodium salt, a phenolic compound, is superior to norepinephrine in reversing cardiovascular collapse, hepatic mitochondrial dysfunction and lactic acidemia in Pseudomonas aeruginosa septic shock in dogs.

Mink, Steven; Roy Chowdhury, Subir K; Gotes, Jose; Cheng, Zhao-Qin; Kasian, Krika; Fernyhough, Paul

Mink, Steven; Roy Chowdhury, Subir K; Gotes, Jose; Cheng, Zhao-Qin; Kasian, Krika; Fernyhough, Paul.

Afiliación

Mink S; Departments of Medicine and Pharmacology and Therapeutics, University of Manitoba, Winnipeg, MB, Canada. minksn@cc.umanitoba.ca.
Roy Chowdhury SK; Health Sciences Centre, GF-221, 820 Sherbrook St, Winnipeg, MB, R3A-1R9, Canada. minksn@cc.umanitoba.ca.
Gotes J; Division of Neurodegenerative Disorders at the St. Boniface Hospital Research Centre, Winnipeg, MB, Canada.
Cheng ZQ; Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico.
Kasian K; Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, Manitoba, Canada.
Fernyhough P; Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

Intensive Care Med Exp ; 4(1): 24, 2016 Dec.

Article en En | MEDLINE | ID: mdl-27456956

Palabras clave

ATP; Antioxidants; Electron transport chain; Gentisic acid; Infection; Lactic acidosis; Mitochondria; Norepinephrine; Septic shock; Vasodilation; Vasopressors

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Intensive Care Med Exp Año: 2016 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Alemania

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