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Asymmetric dimethylarginine (ADMA): will be or will not be a new revolutionary biomarker of bronchial asthma?
Calabrese, C; Carpagnano, G E; Patella, V; Vatrella, A; Santus, P.
Afiliación
  • Calabrese C; Department of Cardio-Thoracic and Respiratory Sciences, Second University of Naples, Naples, Italy - ceciliacalabrese123@gmail.com.
Minerva Med ; 106(5 Suppl 1): 9-11, 2015 Oct.
Article en En | MEDLINE | ID: mdl-27427261
Carraro et al. measured asymmetric dimethylarginine (ADMA) in the exhaled breath condensate (EBC) obtained from children with asthma and from healthy subjects. The authors demonstrated higher levels of ADMA in EBC of asthmatics compared to controls. ADMA levels in EBC did not correlate with serum levels, lung function parameters, and fractional exhaled nitric oxide. ADMA levels in EBC did not significantly differ between asthmatic patients regularly treated with inhaled steroids and those who were steroid naïve. Further studies are necessary in order to evaluate the role of this biomarker in the characterization of phenotypes of severe bronchial asthma.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arginina / Asma / Espiración / Inhibidores Enzimáticos Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Child / Humans Idioma: En Revista: Minerva Med Año: 2015 Tipo del documento: Article Pais de publicación: Italia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arginina / Asma / Espiración / Inhibidores Enzimáticos Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Child / Humans Idioma: En Revista: Minerva Med Año: 2015 Tipo del documento: Article Pais de publicación: Italia