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Relation between clinical risk factors, early cortical changes, and neurodevelopmental outcome in preterm infants.
Kersbergen, Karina J; Leroy, François; Isgum, Ivana; Groenendaal, Floris; de Vries, Linda S; Claessens, Nathalie H P; van Haastert, Ingrid C; Moeskops, Pim; Fischer, Clara; Mangin, Jean-François; Viergever, Max A; Dubois, Jessica; Benders, Manon J N L.
Afiliación
  • Kersbergen KJ; Department of Neonatology, Wilhelmina Children's Hospital and Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Leroy F; INSERM, Cognitive Neuroimaging Unit U992, CEA, Neurospin Center, Saclay, France; University Paris Sud, Orsay; University Paris Saclay, Gif-sur-Yvette, France.
  • Isgum I; Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Groenendaal F; Department of Neonatology, Wilhelmina Children's Hospital and Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
  • de Vries LS; Department of Neonatology, Wilhelmina Children's Hospital and Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Claessens NHP; Department of Neonatology, Wilhelmina Children's Hospital and Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
  • van Haastert IC; Department of Neonatology, Wilhelmina Children's Hospital and Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Moeskops P; Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Fischer C; University Paris Sud, Orsay; University Paris Saclay, Gif-sur-Yvette, France; CEA, NeuroSpin Center, UNATI, Saclay, France.
  • Mangin JF; University Paris Sud, Orsay; University Paris Saclay, Gif-sur-Yvette, France; CEA, NeuroSpin Center, UNATI, Saclay, France.
  • Viergever MA; Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Dubois J; INSERM, Cognitive Neuroimaging Unit U992, CEA, Neurospin Center, Saclay, France; University Paris Sud, Orsay; University Paris Saclay, Gif-sur-Yvette, France.
  • Benders MJNL; Department of Neonatology, Wilhelmina Children's Hospital and Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands; Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom. Electronic a
Neuroimage ; 142: 301-310, 2016 Nov 15.
Article en En | MEDLINE | ID: mdl-27395393
Cortical folding mainly takes place in the third trimester of pregnancy and may therefore be influenced by preterm birth. The aim of this study was to evaluate the development of specific cortical structures between early age (around 30weeks postmenstrual age) and term-equivalent age (TEA, around 40weeks postmenstrual age) in 71 extremely preterm infants, and to associate this to clinical characteristics and neurodevelopmental outcome at two years of age. First, analysis showed that the central sulcus (CS), lateral fissure (LF) and insula (INS) were present at early MRI in all infants, whereas the other sulci (post-central sulcus [PCS], superior temporal sulcus [STS], superior [SFS] and inferior [IFS] frontal sulcus) were only seen in part of the infants. Relative growth from early to TEA examination was largest in the SFS. A rightward asymmetry of the surface area was seen in development between both examinations except for the LF, which showed a leftward asymmetry at both time points. Second, lower birth weight z-score, multiple pregnancy and prolonged mechanical ventilation showed negative effects on cortical folding of the CS, LF, INS, STS and PCS, mainly on the first examination, suggesting that sulci developing the earliest were the most affected by clinical factors. Finally, in this cohort, a clear association between cortical folding and neurodevelopmental outcome at two years corrected age was found, particularly for receptive language.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recien Nacido Prematuro / Imagen por Resonancia Magnética / Corteza Cerebral / Desarrollo Infantil Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Child, preschool / Female / Humans / Male / Newborn Idioma: En Revista: Neuroimage Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recien Nacido Prematuro / Imagen por Resonancia Magnética / Corteza Cerebral / Desarrollo Infantil Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Child, preschool / Female / Humans / Male / Newborn Idioma: En Revista: Neuroimage Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos