Predicting subtype selectivity of dopamine receptor ligands with three-dimensional biologically relevant spectrum.

Kuang, Zheng-Kun; Feng, Shi-Yu; Hu, Ben; Wang, Dong; He, Song-Bing; Kong, De-Xin

Kuang, Zheng-Kun; Feng, Shi-Yu; Hu, Ben; Wang, Dong; He, Song-Bing; Kong, De-Xin.

Afiliación

Kuang ZK; State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Feng SY; Agricultural Bioinformatics Key Laboratory of Hubei Province, College of informatics, Huazhong Agricultural University, Wuhan, China.
Hu B; Agricultural Bioinformatics Key Laboratory of Hubei Province, College of informatics, Huazhong Agricultural University, Wuhan, China.
Wang D; State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
He SB; Agricultural Bioinformatics Key Laboratory of Hubei Province, College of informatics, Huazhong Agricultural University, Wuhan, China.
Kong DX; Agricultural Bioinformatics Key Laboratory of Hubei Province, College of informatics, Huazhong Agricultural University, Wuhan, China.

Chem Biol Drug Des ; 88(6): 859-872, 2016 Dec.

Article en En | MEDLINE | ID: mdl-27390270

Asunto(s)

Receptores Dopaminérgicos/metabolismo; Ligandos; Modelos Químicos; Relación Estructura-Actividad Cuantitativa; Receptores Dopaminérgicos/clasificación; Máquina de Vectores de Soporte

Palabras clave

QSAR; BRS-3D; dopamine receptor; subtype selectivity; support vector machine

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Dopaminérgicos Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Chem Biol Drug Des Asunto de la revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google