Drug-specific CD4<sup>+</sup> T-cell immune responses are responsible for antituberculosis drug-induced maculopapular exanthema and drug reaction with eosinophilia and systemic symptoms syndrome.

Ye, Y-M; Hur, G-Y; Kim, S-H; Ban, G-Y; Jee, Y-K; Naisbitt, D J; Park, H-S; Kim, S-H

Drug-specific CD4⁺ T-cell immune responses are responsible for antituberculosis drug-induced maculopapular exanthema and drug reaction with eosinophilia and systemic symptoms syndrome.

Ye, Y-M; Hur, G-Y; Kim, S-H; Ban, G-Y; Jee, Y-K; Naisbitt, D J; Park, H-S; Kim, S-H.

Afiliación

Ye YM; Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Hur GY; Department of Internal Medicine, College of Medicine, Korea University, Seoul, South Korea.
Kim SH; Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea.
Ban GY; Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Jee YK; Department of Internal Medicine, Dankook University College of Medicine, Cheonan, South Korea.
Naisbitt DJ; MRC Centre for Drug Safety Science, Department of Clinical and Molecular Pharmacology, The University of Liverpool, Liverpool, U.K.
Park HS; Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Kim SH; Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.

Br J Dermatol ; 176(2): 378-386, 2017 Feb.

Article en En | MEDLINE | ID: mdl-27373553

Asunto(s)

Antituberculosos/efectos adversos; Linfocitos T CD4-Positivos/inmunología; Síndrome de Hipersensibilidad a Medicamentos/inmunología; Exantema/inducido químicamente; Inmunidad Celular/inmunología; Adulto; Antituberculosos/inmunología; Exantema/inmunología; Femenino; Antígenos HLA/efectos de los fármacos; Antígenos HLA/inmunología; Humanos; Isoniazida/efectos adversos; Isoniazida/inmunología; Masculino; Persona de Mediana Edad; Rifampin/efectos adversos; Rifampin/inmunología

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Exantema / Síndrome de Hipersensibilidad a Medicamentos / Inmunidad Celular / Antituberculosos Tipo de estudio: Diagnostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Dermatol Año: 2017 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Reino Unido

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