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MNK Inhibition Disrupts Mesenchymal Glioma Stem Cells and Prolongs Survival in a Mouse Model of Glioblastoma.
Bell, Jonathan B; Eckerdt, Frank D; Alley, Kristen; Magnusson, Lisa P; Hussain, Hridi; Bi, Yingtao; Arslan, Ahmet Dirim; Clymer, Jessica; Alvarez, Angel A; Goldman, Stewart; Cheng, Shi-Yuan; Nakano, Ichiro; Horbinski, Craig; Davuluri, Ramana V; James, C David; Platanias, Leonidas C.
Afiliación
  • Bell JB; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Eckerdt FD; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Alley K; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Magnusson LP; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Hussain H; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Bi Y; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Arslan AD; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Clymer J; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Division of Hematology/Oncology/Stem Cell Transplantation, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
  • Alvarez AA; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Goldman S; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Division of Hematology/Oncology/Stem Cell Transplantation, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
  • Cheng SY; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Nakano I; Department of Neurosurgery and Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama.
  • Horbinski C; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Department of Pathology, Feinberg School of Medicine, Northwestern Univer
  • Davuluri RV; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • James CD; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Platanias LC; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Department of Medicine, Jesse Brown VA Medical Cente
Mol Cancer Res ; 14(10): 984-993, 2016 10.
Article en En | MEDLINE | ID: mdl-27364770

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias Encefálicas / Proteínas Serina-Treonina Quinasas / Niacinamida / Glioblastoma / Péptidos y Proteínas de Señalización Intracelular / Indazoles / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mol Cancer Res Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias Encefálicas / Proteínas Serina-Treonina Quinasas / Niacinamida / Glioblastoma / Péptidos y Proteínas de Señalización Intracelular / Indazoles / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mol Cancer Res Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos