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Three new biphenyls from the twigs of Garcinia tetralata and their anti-tobacco mosaic virus activity.
Hu, Qiu-Fen; Wang, Yue-De; Zhu, Dong-Lai; Yu, Zhen-Hua; Zhan, Jian-Bo; Xing, Huan-Huan; Ma, Hang-Ying; Yang, Yan; Li, Yin-Ke; Chen, Zhang-Yu; Gao, Xue-Mei.
Afiliación
  • Hu QF; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming 650031 , China.
  • Wang YD; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming 650031 , China.
  • Zhu DL; b Technology Center , China Tobacco Yunnan Industry Company (Ltd.) , Kunming 650000 , China.
  • Yu ZH; b Technology Center , China Tobacco Yunnan Industry Company (Ltd.) , Kunming 650000 , China.
  • Zhan JB; b Technology Center , China Tobacco Yunnan Industry Company (Ltd.) , Kunming 650000 , China.
  • Xing HH; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming 650031 , China.
  • Ma HY; b Technology Center , China Tobacco Yunnan Industry Company (Ltd.) , Kunming 650000 , China.
  • Yang Y; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming 650031 , China.
  • Li YK; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming 650031 , China.
  • Chen ZY; c College of Resource and Environment , Yuxi Normal University , Yuxi 653100 , China.
  • Gao XM; b Technology Center , China Tobacco Yunnan Industry Company (Ltd.) , Kunming 650000 , China.
J Asian Nat Prod Res ; 18(12): 1115-1121, 2016 Dec.
Article en En | MEDLINE | ID: mdl-27314454
Phytochemical investigations on the ethanol extract of the twigs of Garcinia tetralata resulted in the isolation of three new biphenyls, tetralatabiphenyls A-C (1-3), along with three known biphenyl derivatives (4-6). Structural elucidations of 1-3 were performed by spectroscopic methods such as 1D and 2D NMR spectra, in addition to high-resolution mass spectra. Compounds 1-6 were also evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 3 showed high anti-TMV activity with inhibition rate of 31.1%. Compounds 1, 2, and 4-6 also showed modest anti-TMV activities with inhibition rates in the range of 18.9-24.5%, respectively.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Virus del Mosaico del Tabaco / Compuestos de Bifenilo / Garcinia Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Virus del Mosaico del Tabaco / Compuestos de Bifenilo / Garcinia Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido