[THE CORRECTION OF THE LOCAL IMMUNE RESPONSE AT THE PATIENTS WITH HELICOBACTER PYLORI INFECTION].
Eksp Klin Gastroenterol
; (2): 30-4, 2016.
Article
en Ru
| MEDLINE
| ID: mdl-27301114
INTRODUCTION: Helicobacter pylori infection is due to the high prevalence in population attracts the clinical interest of researchers in the whole World. It is well known that this microorganism not only resides in the mucosa of the gastrointestinal tract, but is also defined in the periodontal pocket of the oral cavity. THE AIM OF INVESTIGATION: to evaluate Helicobacter pylori diagnostics in the mouth and prove a method of relief of the inflammatory process by applying immunomodulator Imudon. RESULTS. On the basis of obtained results it was found that the inclusion of topical immunomodulator Imudon in the complex therapy of Helicobacter pylori-associated diseases leads to reduction of inflammatory potential through the decrease of the TNFα, IL-6 activity in saliva and to increase the protective properties of saliva as a result of increased levels of mucin, significantly reduces the frequency of relapses in the one year after therapy. CONCLUSION: It is practically important to determine the effectiveness of eradication therapy by the study of the contents of the tooth-gingival pocket for the detection of genetic material of Helicobacter pylori, as well as to include in the complex therapy of Helicobacter pylori-associated diseases of the immune modulator Imudon.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Saliva
/
Timerosal
/
Helicobacter pylori
/
Infecciones por Helicobacter
/
Inmunidad Mucosa
/
Úlcera Duodenal
/
Antígenos Bacterianos
/
Antígenos Fúngicos
Tipo de estudio:
Clinical_trials
/
Risk_factors_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
Ru
Revista:
Eksp Klin Gastroenterol
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2016
Tipo del documento:
Article
Pais de publicación:
Rusia