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Carcinoma ex pleomorphic adenoma of the parotid gland: a multi-institutional retrospective analysis in the Northern Japan Head and Neck Cancer Society.
Suzuki, Masahiro; Matsuzuka, Takashi; Saijo, Satoshi; Takahara, Miki; Harabuchi, Yasuaki; Okuni, Tsuyoshi; Himi, Tetsuo; Kakizaki, Tomohiko; Fukuda, Satoshi; Yamada, Kazuyuki; Nagahashi, Tatsumi; Abe, Takahisa; Shinkawa, Hideichi; Katagiri, Katsunori; Sato, Hiroaki; Fukui, Naoko; Ishikawa, Kazuo; Suzuki, Takahiro; Kobayashi, Toshimitsu; Saito, Daisuke; Saijo, Shigeru; Tateda, Masaru; Hashimoto, Sho; Ishida, Akihiro; Kakehata, Seiji; Suzuki, Osamu; Hashimoto, Yuko; Omori, Koichi.
Afiliación
  • Suzuki M; a Department of Otolaryngology , Fukushima Medical University School of Medicine , Fukushima , Japan.
  • Matsuzuka T; a Department of Otolaryngology , Fukushima Medical University School of Medicine , Fukushima , Japan.
  • Saijo S; a Department of Otolaryngology , Fukushima Medical University School of Medicine , Fukushima , Japan.
  • Takahara M; b Department of Otolaryngology-Head , Neck Surgery, Asahikawa Medical University , Hokkaidou , Japan.
  • Harabuchi Y; b Department of Otolaryngology-Head , Neck Surgery, Asahikawa Medical University , Hokkaidou , Japan.
  • Okuni T; c Department of Otolaryngology , Sapporo Medical University School of Medicine , Hokkaidou , Japan.
  • Himi T; c Department of Otolaryngology , Sapporo Medical University School of Medicine , Hokkaidou , Japan.
  • Kakizaki T; d Department of Otolaryngology-Head and Neck Surgery , Hokkaido University Graduate School of Medicine , Hokkaidou , Japan.
  • Fukuda S; d Department of Otolaryngology-Head and Neck Surgery , Hokkaido University Graduate School of Medicine , Hokkaidou , Japan.
  • Yamada K; e Department of Otolaryngology, Head and Neck Surgery , National Hospital Organization Hokkaido Cancer Center , Hokkaidou , Japan.
  • Nagahashi T; e Department of Otolaryngology, Head and Neck Surgery , National Hospital Organization Hokkaido Cancer Center , Hokkaidou , Japan.
  • Abe T; f Department of Otorhinolaryngology , Hirosaki University Graduate School of Medicine , Hokkaidou , Japan.
  • Shinkawa H; f Department of Otorhinolaryngology , Hirosaki University Graduate School of Medicine , Hokkaidou , Japan.
  • Katagiri K; g Department of Otolaryngology , Iwate Medical University , Morioka-shi , Japan.
  • Sato H; g Department of Otolaryngology , Iwate Medical University , Morioka-shi , Japan.
  • Fukui N; h Department of Otorhinolaryngology and Head and Neck Surgery , Akita University Graduate School of Medicine , Akita-shi , Japan.
  • Ishikawa K; h Department of Otorhinolaryngology and Head and Neck Surgery , Akita University Graduate School of Medicine , Akita-shi , Japan.
  • Suzuki T; i Department of Otolaryngology, Head and Neck Surgery , Tohoku University School of Medicine , Sendai-shi , Japan.
  • Kobayashi T; i Department of Otolaryngology, Head and Neck Surgery , Tohoku University School of Medicine , Sendai-shi , Japan.
  • Saito D; j Department of Head and Neck Surgery , Miyagi Cancer Center , Natori-shi , Japan.
  • Saijo S; j Department of Head and Neck Surgery , Miyagi Cancer Center , Natori-shi , Japan.
  • Tateda M; k Department of Otolaryngology , National Sendai Medical Center , Sendai-shi , Japan.
  • Hashimoto S; k Department of Otolaryngology , National Sendai Medical Center , Sendai-shi , Japan.
  • Ishida A; l Department of Otolaryngology , Yamagata University School of Medicine , Yamagata-shi , Japan.
  • Kakehata S; l Department of Otolaryngology , Yamagata University School of Medicine , Yamagata-shi , Japan.
  • Suzuki O; m Department of Diagnostic Pathology , Fukushima Medical University School of Medicine , Fukushima , Japan.
  • Hashimoto Y; m Department of Diagnostic Pathology , Fukushima Medical University School of Medicine , Fukushima , Japan.
  • Omori K; a Department of Otolaryngology , Fukushima Medical University School of Medicine , Fukushima , Japan.
Acta Otolaryngol ; 136(11): 1154-1158, 2016 Nov.
Article en En | MEDLINE | ID: mdl-27295405
CONCLUSION: The 3-year progression-free survival rate of non-invasive salivary duct carcinoma (SDC) or adenocarcinoma not otherwise specified (NOS) was significantly better than that of invasive SDC or adenocarcinoma NOS in Carcinoma ex pleomorphic adenoma (CXPA). The presence of invasion is an important prognostic factor for SDC and adenocarcinoma NOS in CXPA. OBJECTIVES: CXPA is a rare parotid gland malignant tumor for which therapy is not yet standardized. The purpose of this study was to review the characteristics of CXPA patients and to analyze their outcomes in the Northern Japan Head and Neck Cancer Society. METHOD: The medical records of 33 patients who had been provided initial treatment in 12 institutes of northern Japan from 2002-2011 were reviewed as a multi-institutional retrospective study. RESULTS: The 3-year overall and progression-free survival rate of all patients was 79.9% and 76.8%, respectively. Both the 3-year overall and progression-free survival rates were 87.5% for patients with non-invasive SDC or adenocarcinoma NOS. The 3-year overall and progression-free survival rates for patients with invasive SDC or adenocarcinoma NOS were 60.4% and 30.5%, respectively. The progression-free survival rates for patients with invasive SDC or adenocarcinoma NOS was significantly poor (p < 0.05).
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glándula Parótida / Neoplasias de la Parótida / Carcinoma / Adenoma Pleomórfico Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Acta Otolaryngol Año: 2016 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glándula Parótida / Neoplasias de la Parótida / Carcinoma / Adenoma Pleomórfico Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Acta Otolaryngol Año: 2016 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido