Heat stress in pigs is accompanied by adipose tissue-specific responses that favor increased triglyceride storage.
J Anim Sci
; 94(5): 1884-96, 2016 May.
Article
en En
| MEDLINE
| ID: mdl-27285686
Heat stress (HS) negatively affects all aspects of performance in pigs. Although certain tissue-specific responses in the liver, skeletal muscle, and intestine are known, there is paucity of information on responses within the adipose tissue. Therefore, the objective of this study was to delineate adipose tissue responses during HS in pigs. Thirty crossbred (Ossabaw × Duroc × Landrace) pigs were assigned to 3 treatments for 7 d. Treatments were 1) control and libitum fed (CON) with room temperature set at 20°C ± 1°C, 2) pair fed (PF) with room temperature as the CON treatment but pair fed to HS pigs, and 3) HS with room temperature 35°C ± 1°C and ad libitum access to feed. Compared with CON pigs, HS pigs had decreased feed intake and elevated skin temperature and respiration rate ( < 0.01). Blood urea nitrogen was higher ( = 0.01) in HS pigs compared with CON pigs only in males. In both subcutaneous and mesenteric adipose tissue, mRNA abundance of phosphoenolpyruvate carboxykinase (PCK1) was more elevated ( < 0.01) in HS groups compared with the CON and PF groups. Heat stress also caused increased heat shock protein 70 (HSP70; = 0.067) and CCAT/enhancer-binding homologous protein (CHOP) content ( < 0.05) in the mesenteric fat compared with the CON treatment. In conclusion, induction of PCK1 expression in adipose tissue by HS suggests elevated glyceroneogenesis might be involved in the increased fat storage in pigs under HS.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de los Porcinos
/
Triglicéridos
/
Tejido Adiposo
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Trastornos de Estrés por Calor
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Metabolismo de los Lípidos
Límite:
Animals
Idioma:
En
Revista:
J Anim Sci
Año:
2016
Tipo del documento:
Article
Pais de publicación:
Estados Unidos